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    20 June 2023, Volume 21 Issue 3 Previous Issue    Next Issue
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    EXPERT VIEWPOINT
    Interpretation of Work Plan for Pilot Counties to Promote the Elimination of Schistosomiasis (2023 Edition)
    ZHANG Li-juan, LI Shi-zhen, LI Yin-long, ZHU Hong-qing, CAO Chun-li, XU Jing, LI Shi-zhu
    2023, 21 (3):  121-125.  doi: 10.3969/j.issn.1672-2302.2023.03.001
    Abstract ( 390 )   HTML ( 19 )   PDF (866KB) ( 955 )  

    Work Plan for Pilot Counties to Promote the Elimination of Schistosomiasis (2023 Edition) was issued by National Administration of Disease Control and Prevention on January 2nd, 2023. The program aims to promote elimination of schistosomiasis through pilot implementation, to summarize experience on schistosomiasis elimination and gradually spread the work plan to the whole country. This article interpreted the background, objectives, routine measures, five major promotion measures, assessment indicators and organizational guarantee of this plan to guide the efficient and standardized implementation of schistosomiasis elimination work at the grassroots level.

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    SPECIALARTICLES FOR REGULATIONS ON PREPAREDNESS FOR AND RESPONSE TO EMERGENT PUBLIC HEALTH HAZARDS RELEASED AT 20TH ANNIVERSARY
    Analysis on the epidemiological characteristics of public health emergencies in Jilin Province from 2013 to 2022
    ZHANG Yang, TIAN Xin, ZHAI Qian-qian, TIAN Rui, YAO Lai-shun
    2023, 21 (3):  126-129,159.  doi: 10.3969/j.issn.1672-2302.2023.03.002
    Abstract ( 382 )   HTML ( 15 )   PDF (1793KB) ( 349 )  

    Objective To understand epidemic status and regularity of occurrence of public health emergencies in Jilin Province for evidence in following implementation of corresponding prevention and control measures. Methods The related data on the public health emergencies reported in Jilin Province were recovered from the subsystem of Public Health Emergency Management under the Information System for Disease Prevention and Control in China from 2013 through 2022, and analyzed for the epidemiological characteristics, including event type, time and regional distribution, place of occurrence, using descriptive research method. Results A total of 3 098 public health emergencies were reported in Jilin Province from 2013 to 2022, during which 11 453 cases and 134 deaths were reported. The reporting peak of public health emergencies was from October every year to March the following year, and the number during which accounted for 83.02% (2 572/3 098) of the total reports for public health emergencies. The types of events were mainly associated with environmental events, and the number of events, incidences and deaths reported accounted for 94.19% (2 918/3 098), 58.01% (6 644/11 453) and 78.36% (105/134) of the total public health emergencies, respectively. Except for one water pollution incident, all the other environmental incidents were non-occupational carbon monoxide poisoning. The top three cities in the number of incidents were Changchun (1 865 events, 60.20%), Jilin (900 events, 29.06%) and Yanbian (249 events, 8.04%). In total, 163 events associated with infectious diseases were reported, which involved 4 148 cases and 21 deaths. The event encompassed 13 infectious diseases, among which the top three reported incidents were COVID-19 (97 events, 59.51%), chickenpox (30 events, 18.40%) and hemorrhagic fever (18 events, 11.04%). Fifty-eight events were reported in schools, of which infectious diseases were dominant (47 events,81.04%), and primary schools were the main places that emergencies occurred (29 events, 50.00%). Conclusion In the past years, the public health emergencies in Jilin Province were mainly environmental events, and peaked in winter and spring every year. The findings suggest that, according to the seasonal characteristics of public health emergencies, public publicity and education should be carried out to improve the prevention ability. Infectious diseases were the major public health emergencies in schools, mostly occurring in primary schools. The results suggest that schools should be important sites to implement corresponding prevention and control measures.

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    Analysis on the epidemiological characteristics of public health emergencies in Anhui Province, 2018-2022
    DENG Shu, TENG Xue-jiao, ZHAO Yu-qiu, WU Jia-bing
    2023, 21 (3):  130-134,140.  doi: 10.3969/j.issn.1672-2302.2023.03.003
    Abstract ( 344 )   HTML ( 26 )   PDF (1607KB) ( 420 )  

    Objective To analyze the epidemiological characteristics of public health emergencies in Anhui Province for scientific basis to formulate corresponding prevention and control strategies. Methods The closed public health emergencies reported in Anhui Province from January 2018 to December 2022 were retrieved from the subsystem of Public Health Emergency Management under the Information System for Disease Prevention and Control in China. Descriptive epidemiology was used to analyze the events concerning the grading, category, transmission route and distribution of the time, region and place. Results In total, 1 275 public health emergencies were reported in Anhui from 2018 to 2022, which involved 36 119 cases and 60 deaths. The events were mainly unclassified and at general scale, respectively accounting for 77.65% and 20.94% of the total reports. Infectious diseases were the major events (n=1 200, 94.12%), and respiratory infections were most seen, which accounted for 73.25% (879/1 200) of the total infections. COVID-19, chickenpox and influenza were the main types of infectious diseases reported, accounting for 29.33% (352/1 200), 26.75% (326/1 200) and 12.50% (150/1 200), respectively, followed by sudden incident of poisoning (66 events, 5.18%). Food poisoning most occurred (60.61%, 40/66). The major causes of deaths were involved in fever with thrombocytopenia syndrome (8 cases, 13.33%), haemorrhagic fever (5 cases, 8.33%), accidental ingestion of wild poisonous mushrooms (4 cases, 6.67%) and aluminium phosphide poisoning (4 cases, 6.67%). Temporal distribution showed two peaks that primarily appeared from October to February, and the sub-peak was from April to June. By the number of the incidents reported, the top three cities were Hefei (145 events, 11.37%), Wuhu (138 events, 10.82%) and Ma'anshan (135 events, 10.59%). The sites with higher incidence of the events were schools and childcare institutions, with 764 events (59.92%) and 31 457 cases reported, chickenpox was most reported (321 events, 42.02%), followed by communities/natural villages and households, with 445 events and 3 621 cases reported, and cluster outbreak was associated with COVID-19 (251 events, 56.40%). There was a linear correlation between the timeliness of reporting and the duration of infectious disease and poisoning outbreaks (rs=1.000, 0.998, both P<0.001). Conclusion Public health emergencies in Anhui Province are mainly involved in infectious diseases, and schools and childcare institutions are the key places for prevention and control. Meanwhile, it is necessary to strengthen the monitoring and early warning of public health emergencies such as severe fever with thrombocytopenia syndrome and food poisoning, and reduce the death cases.

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    Analysis on the epidemiological characteristics of public health emergencies in schools in Chongqing Municipality from 2010 to 2022
    YAN Pei-pei, LONG Jiang, LIU Hui-hui, XIONG Ying, XIA Yu
    2023, 21 (3):  135-140.  doi: 10.3969/j.issn.1672-2302.2023.03.004
    Abstract ( 343 )   HTML ( 8 )   PDF (1972KB) ( 511 )  

    Objective To understand the epidemiological characteristics of public health emergencies occurring in schools in Chongqing area for evidence to scientifically deal with the emergencies in school campus. Methods The data on the public health emergencies reported in schools in Chongqing area were retrieved from the subsystem of Public Health Emergency Management under the Information System for Disease Prevention and Control in China from January 2010 to December 2022, and analyzed for the epidemic characteristics using descriptive epidemiology. Results A total of 3 162 emergencies in school campus were reported from 2010 to 2022, accounting for 79.23% (3 162/3 991) of all emergencies reported in Chongqing. In total, 85 889 cases and 5 deaths were reported. Of the emergencies reported, 3 120 were associated with infectious diseases. The top three infectious diseases reported were varicella (40.16%, 1 253/3 120), hand-foot-and-mouth disease (20.83%, 650/3 120) and mumps (11.70%, 365/3 120). School emergencies were reported every year in Chongqing from 2010 to 2022, and the annual number of reported emergencies ranged from 132 to 453. The seasonal distribution indicated bimodal trend, and annual peak of reported emergencies basically appeared in May and November. The top three areas with reported emergencies were Kaizhou District (292 events, 9.23%), Hechuan District (166 events, 5.25%) and Yunyang County (163 events, 5.15%). The emergency primarily occurred in primary schools (1 664 events, 52.62%) and nurseries (911 events, 28.81%). The duration of insect-borne infectious disease was the longest, which lasted for 32.07 (31.21, 32.92) days. Management of the respiratory infectious diseases was the longest, and the emergency scale was the largest, which accounted for 9.71 (4.29, 16.63) days and 23 (14, 38) cases, respectively. Conclusion Currently, infectious diseases are the key to prevention and control of public health emergencies in schools in Chongqing. Monitoring should fall on the emergencies occurring nurseries and primary schools. Various prevention and control measures should be implemented in order to eventually reduce the occurrence and impact of school emergencies.

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    Analysis on the epidemiological characteristics of public health emergencies from intestinal infectious in schools in Hunan Province from 2004 to 2022
    YUE Wen-fang, LIU Fu-qiang, DUAN Hong-ying, XIA Meng-zhi, CAI Fu-wen, ZHANG Si-yu
    2023, 21 (3):  141-145,154.  doi: 10.3969/j.issn.1672-2302.2023.03.005
    Abstract ( 298 )   HTML ( 11 )   PDF (1650KB) ( 338 )  

    Objective To investigate the epidemiological features of public health emergencies arising from intestinal infectious diseases in schools in Hunan Province for scientific evidence to formulate effective prevention and control measures against the urgent events. Methods The information on public health emergencies associated with infectious diseases reported in schools in Hunan Province was collected from 2004 to 2022, and analyzed pertinent to the time, regional and population distribution using descriptive epidemiological method. Results From 2004 to 2022, a total of 329 public health emergencies caused by intestinal infectious diseases in schools were reported in Hunan Province. In total, 14 506 cases were reported, yet no death occurred. The incident level was generally at grade Ⅳ (225 events, 68.39%) and ungraded (99 events, 30.09%). Of the 5 types of diseases involved, other infectious diarrhea was most seen (153 events, 46.50%), followed by hand-foot-and-mouth disease (82 events, 24.92%). The number of incidents was the highest in 2018 (50 events, 15.20%), and higher time distribution was from March to June and September to December. The emergencies were reported in 14 cities (prefectures) across the province, with the highest incidents (60 events,18.24%) and cases (3 251 cases, 22.41%) reported in Changsha. Most of the incidents occurred in kindergartens (91 events, 27.66%), followed by in elementary schools (86 events, 26.14%) and junior high schools (41 events, 12.46%). The attack rate in the three types of sites aforementioned was higher in rural area than in urban area. The main causes of public health emergencies from intestinal infectious diseases in schools were involved in transmission from close contact (40.73%, 134/329) and contamination of water source (25.23%, 83/329). Delayed report would result in longer duration of the incident (r=0.88, P< 0.01). Conclusion The key institutions for the prevention and control of public health emergencies caused by intestinal infectious diseases in schools in Hunan Province are involved in kindergartens, primary schools and junior high schools, and the critical periods for prevention and control of the emergencies are spring, autumn and winter seasons. The prevention and control measures should target at safe supply of the food and drinking water in schools, practicing daily disinfection, regular examination in the morning and afternoon for the students, registration and tracking of the students absent from school due to illness so as to reduce the occurrence of public health emergencies caused by intestinal infectious diseases in school campus.

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    Analysis on the epidemiological characteristics of brucellosis related public health emergencies in Shandong Province from 2012 to 2022
    YU Xiao-lin, LI Qun, PEI Ying-xin
    2023, 21 (3):  146-149.  doi: 10.3969/j.issn.1672-2302.2023.03.006
    Abstract ( 271 )   HTML ( 8 )   PDF (851KB) ( 443 )  

    Objective To analyze the epidemiological characteristics of public health emergencies caused by brucellosis in Shandong Province, so as to provide reference for the prevention and control of this infectious disease throughout the province. Methods The brucellosis related public health emergencies reported in Shangdong Province from 2012 to 2022 were initially collected through the subsystem of Public Health Emergency Management under the Information System for Disease Prevention and Control in China, and then analyzed pertaining to distribution of region, time and population of the events as well as the root cause for the infection using descriptive epidemiology. Results From 2012 to 2022, a total of 243 public health emergencies resulted from brucellosis were reported in Shandong Province, with 782 individuals affected and no death. The emergencies were most reported in Jining City and Dezhou City, respectively accounting for 64 (26.34%) and 63 (25.93%). The events generally occurred in between May and July, with a total of 100 events reported (41.15%). The reported cases were mainly males (561 cases, 71.74%), and the patients' age ranged from 40 and 69 years old (575 cases, 73.53%). Farmers were most affected by the infection (682 cases, 87.21%). The main places where the incident occurred were households (172 events, 70.78%) and rural villages (56 events, 23.05%). The top two causes for the emergencies were transmission via life contact (89 events, 36.63%) and vector animal transmission (82 events, 33.74%). Conclusion Shandong Province is an area with a high risk of sudden public health emergencies related to brucellosis in China. The findings suggest that it is necessary to further strengthen health education in key areas and populations, monitor and warn of brucellosis incidents, and reduce the occurrence of brucellosis incidents.

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    Analysis on the epidemiological characteristics of public health emergencies from food poisoning in Chongqing Municipality from 2010 to 2022
    DUAN Chen-lin, ZHOU Lei, LIU Hui-hui, LUO Shu-quan, LONG Jiang
    2023, 21 (3):  150-154.  doi: 10.3969/j.issn.1672-2302.2023.03.007
    Abstract ( 494 )   HTML ( 10 )   PDF (1619KB) ( 785 )  

    Objective To understand the patterns and characteristics of public health emergencies arising from food poisoning in Chongqing Municipality so as to provide a scientific basis for promoting effective prevention and control of similar events. Methods The related data on the public health emergencies caused by from food poisoning reported in Chongqing were collected from January 2010 to December 2022 via the subsystem of Public Health Emergency Management under the Information System for Disease Prevention and Control in China, and descriptively analyzed pertinent to the epidemiological characteristics, including the time, places and pathogenic factors of the events. Results One hundred and sixteen events of food poisoning were reported in Chongqing from 2010 to 2022, which affected 3 415 people and resulted in 22 deaths. Food poisoning caused by bacteria was most seen (59 events, 50.86%), and affected most people (2 494 cases, 73.03%). Vibrio parahaemolyticus and Salmonella were the major pathogenic bacteria in the incidents, and responsible for 41 events and 1 720 cases of the food poisoning, respectively accounting for 69.49% and 68.97% of the bacterial food poisoning. Food poisoning caused by fungi led to the highest number of deaths (10 cases, 45.45%), all of the deaths were resulted from accidental ingestion of poisonous mushrooms. The peak of food poisoning incidents in Chongqing chiefly appeared in May and September, during which period 40 incidents (34.48%) were reported, with 1 378 poisoning cases (40.35%) involved. From 2010 to 2022, the top three districts (counties) in Chongqing with the incidents reported were Jiulongpo District (13 events), Changshou District (12 events) and Qianjiang District (8 events). Sixty-eight events (58.62%) of food poisoning in rural areas in Chongqing were reported from 2010 to 2022, which involved 1 831 people (53.62%). The incidents primarily occurred in households, with 39 events reported. Forty-eight (41.38%) incidents of food poisoning were reported in urban areas, which affected 1 584 people (46.38%). The incidents largely occurred in business providing catering services, with 27 events. All 22 deaths from food poisoning occurred in rural households. Conclusion In the summer and autumn when food poisoning is high, monitoring over the food safety should be intensified in key areas besides provision of education on food safety and health, improving the ability to recognize native common toxic chemicals, differentiate poisonous plants and mushrooms in local residents so as to prevent food poisoning incidents.

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    Analysis on the epidemiological characteristics of public health emergencies in Hefei City from 2011 to 2020
    ZHAO Ke-fu, WANG Wen-Jing, WU Jin-ju, LIU Xu-xiang
    2023, 21 (3):  155-159.  doi: 10.3969/j.issn.1672-2302.2023.03.008
    Abstract ( 295 )   HTML ( 9 )   PDF (1385KB) ( 630 )  

    Objective To understand the epidemiological characteristics of public health emergencies in Hefei for scientific evidence to respond to prevention and control of such emergencies in the future. Methods The data on the public health emergencies reported in Hefei area between January 1, 2011 and December 31, 2020 were initially retrieved from the subsystem of Public Health Emergency Management under the Information System for Disease Prevention and Control in China, and then descriptively analyzed concerning the emergency grades, classification, distribution of areas, places and time. Results In total, 190 emergencies were reported in Hefei from 2011 to 2020, and most of the emergencies were ungraded (61.58%, 117/190). A total of 5 323 cases and 31 deaths were reported. The emergencies were involved in infectious diseases (81.58%, 155/190), followed by food poisoning (9.47%, 18/190). The cases of death caused by environmental factors events was the highest (48.39%, 15/31), followed by occupational poisoning events (22.58%, 7/31). The events of infectious diseases mostly occurred from November to February of following year (72.90%, 113/155), and food poisoning was most reported between May and July (55.56%, 10/18). In the 8 incidents of occupational poisoning, 4 occurred in September. From 2011 to 2020, the emergencies were reported in all counties (cities and districts) in Hefei. Baohe District had the highest reports of emergencies, accounting for 22.11% (42/190) of the total emergencies reported across the city. 56.32% (107/190) of emergencies occurred in schools, in which 50.47% (54/107) were in primary schools. Infectious diseases were the major emergencies in schools (94.39%, 101/107). The top three diseases involved in emergencies in schools were chicken pox, other infections diarrhea and influenza, accounting for 38.31% (41/107), 21.50% (23/107) and 14.02% (15/107), respectively. Conclusion In recent years, infectious disease events are the main types of emergencies in Hefei, and schools are the major places where emergencies occur. Environmental factors and occupational poisoning are the important factors leading to deaths. It is recommended to strengthen the monitoring and management of infectious diseases in schools as well as improve the emergency response capacity and the treatment level of poisoning personnel.

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    Analysis on the epidemiological patterns of public health emergencies in Changchun City from 2004 to 2022
    YIN Yuan, WU Hui, WANG Yue, ZHOU Yu-xiang, REN Zhi-xing
    2023, 21 (3):  160-163.  doi: 10.3969/j.issn.1672-2302.2023.03.009
    Abstract ( 335 )   HTML ( 10 )   PDF (1318KB) ( 411 )  

    Objective To analyze the epidemiological characteristics of public health emergencies in Changchun City for evidence to develop corresponding prevention and control measures. Methods The public health emergencies reported in Changchun City from January 1, 2004 to December 31, 2022 were recovered from the subsystem of Public Health Emergency Management under the Information System for Disease Prevention and Control in China, and descriptively investigated concerning the grades, classification, distribution of the time, regions and places of the emergencies. Results A total of 3 070 public health emergencies were reported in Changchun City from 2004 through 2022, during which 8 164 cases and 198 deaths were reported. The emergencies were primarily ungraded events(n=3 031, 98.73%), and the rest were crises at general or larger scale, which involved 29 (0.94%) and 10 (0.33%), respectively. The number of events (n=2 858, 93.09%) and deaths (n=165, 83.33%) of environmental factors were the highest, followed by infectious diseases, with 195 events (6.35%) and 29 deaths (14.65%). The environmental factors were mainly non-occupational carbon monoxide poisoning, and the number of events and deaths accounted for 99.90% (2 855/2 858) and 100.00% (165/165) of the environmental factors, respectively. Infectious disease events were dominated by influenza A (H1N1), accounting for 60.00% (117/195) of infectious disease events. The highest number of deaths was epidemic hemorrhagic fever, accounting for 48.28% (14/29) of infectious disease events.The number of reported incidents was mainly in Chaoyang District (n=1 490), Dehui City (n=356) and Erdao District (n=334), which accounted for 71.01% of the total events. The peak of the emergency appeared from October to March of the following year, when a total of 2 589 events (84.33%) were reported. The incidents primarily occurred in families (n=2 663, 86.74%) and schools (n=128, 4.17%). Conclusion The events from non-occupational carbon monoxide poisoning should be the focus of prevention and control of public health emergencies in Changchun City, particularly the safety of self-heating in winter season. In addition, publicity and education in communities and schools should be strengthened, and the awareness of prevention in population should be raised in order to reduce the occurrence of public health emergencies.

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    Analysis on the epidemiological characteristics of public health emergencies in schools in Changsha from 2012 to 2022
    ZHAO Jin, HU Wei-hong, ZHANG Si-yu, LUO Piao-yi, KUANG Wen-tao, NI Han, ZHA Wen-ting, YI Shang-hui, LÜ Yuan
    2023, 21 (3):  164-168.  doi: 10.3969/j.issn.1672-2302.2023.03.010
    Abstract ( 280 )   HTML ( 5 )   PDF (2028KB) ( 464 )  

    Objective To analyze the occurrence regularity and characteristics of public health emergencies in schools in Changsha City for scientific basis for urgent response to public health emergencies in schools. Methods The public health emergencies in schools reported in Changsha from 2012 to 2022 were obtained from the subsystem of Public Health Emergency Management under the Information System for Disease Prevention and Control in China, and descriptively investigated regarding the number of the emergencies, grades, categories, the number of patients, distribution of time and places. Results In total, 293 public health emergencies in schools were reported in Changsha from 2012 to 2022, which involved 14 416 cases. No death occurred. Of the emergencies, 179 were in grade Ⅳ, and 114 ungraded. No grade Ⅲ or above emergency was reported. In the 293 emergencies, 288 were associated with infectious disease, one was involved in poisoning, and 4 were associated with other public health emergency, with 14 320 cases reported. In the school infectious disease incident, the top three events were varicella (35.07%,101/288), mumps (28.13%,81/288), and influenza (21.53%,62/288), yet the top three of the incidence number was influenza (38.16%,5 464/14 320), mumps (27.14%,3 886/14 320), and varicella (22.47%,3 217/14 320). Two peaks appeared in April-May and November-December throughout the year. The emergencies were most reported in primary schools, followed by kindergartens and junior high schools, respectively accounting for 72.01% (211/293), 10.92% (32/293) and 9.22% (27/293) of the total events reported in schools. Liuyang City ranked the first in the number of reported emergencies and incidences, accounting respectively for 43.00% (126/293) and 37.37% (5 387/14 416) of the total number of school reports. The number of reported emergencies and incidences was the lowest in Furong District, which respectively accounted for 2.05% (6/293) and 0.90% (130/14 416) of the total reports. Conclusion Infectious diseases associated with respiratory system should be responsible for the public health emergencies in schools in Changsha, and primary schools appears to be most affected. The findings suggest that targeted measures should be developed in the prevention and control efforts, and vaccination shall be expanded in order to reduce the occurrence of public health emergencies in school campus.

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    CLINICAL STUDIES
    Analysis of hepatic features on CT imaging in children of paragonimiasis
    LI Xiang, FU Xu-wen, XU Yan-ling, WEI Jia-lu, QI Min, GAN Wei, HUANG Ying
    2023, 21 (3):  169-173.  doi: 10.3969/j.issn.1672-2302.2023.03.011
    Abstract ( 416 )   HTML ( 4 )   PDF (6158KB) ( 713 )  

    Objective To investigate the demonstration CT imaging of hepatic in children with paragonimiasis for improving understanding of the imaging manifestations of this disease. Methods Retrospective analysis was performed regarding the general information, laboratory findings and CT images in children confirmed or clinically diagnosed as paragonimiasis in Kunming Third People's Hospital between 2019 and 2021. The cases were divided into two groups according to the presence of liver lesions identified on abdominal CT, with the general condition and laboratory findings of the two groups compared, and the CT imaging of children with liver lesions was analyzed. Results A total of 63 children were included in the analysis, 19 (30.2%) had liver lesions, and another 44 (69.8%) had no liver lesions. The percentage of peripheral blood eosinophils was higher in children with liver lesions [46.39% (27.81%, 59.53%)] than in children without liver lesions [26.62% (18.42%, 46.70%)](Z=2.022, P<0.05), yet the ratio of serum albumin to globulin in children with liver lesions was lower than in children without liver lesions [0.80 (0.70, 1.00) vs. 1.00 (0.80, 1.20); Z=-1.997, P<0.05]. In the 19 children with liver lesions, 13 (68.4%) had multiple lesions, 6 (31.6%) had a single lesion, 16 (84.2%) had "worm tunnel sign", 5 (26.3%) had abscess, and 5 (26.3%) had "mushroom sign". In addition, all children with liver lesions were complicated with pleural effusion and pulmonary consolidation. Four children (21.1%) were complicated with skin and soft tissue swelling, and 2 (10.5%) demonstrated hypodensity in the cerebral parenchyma. Conclusion Nearly one-third of children with paragonimiasis are complicated with liver lesions, and the presence of "worm tunnel sign", abscess and "mushroom sign" of CT-enhanced scan is of higher diagnostic value for hepatic paragonimiasis.

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    Clinical distribution and drug resistance of Staphylococcus aureus isolates from inpatients
    XU Bei, LI Ping, ZHANG Qing-song
    2023, 21 (3):  174-177.  doi: 10.3969/j.issn.1672-2302.2023.03.012
    Abstract ( 401 )   HTML ( 13 )   PDF (901KB) ( 511 )  

    Objective To investigate the patterns of clinical distribution and drug resistance of Staphylococcus aureus strains isolated from hospitalized patients in a hospital for scientific evidence in the treatment of the infection in clinic. Methods Patients with Staphylococcus aureus infection treated in XuanCheng City Central Hospital were included from September 2021 to March 2023 as study subjects. The resistance genes mecA and Panton-Valentine leukocidin (PVL) of Staphylococcus aureus were detected by polymerase chain reaction (PCR), SPSS 20.0 and WHONET 5.6 software was used to analyze the clinical distribution patterns and drug resistance status of Staphylococcus aureus infection. Results A total of 133 patients with Staphylococcus aureus infections were included in the analysis. Among single department, the top two departments were Pulmonary and Critical Care Medicine (21.8%, 29/133) and the Intensive Care Unit (18.8%, 25/133). The major types of infection were skin furuncle & carbuncle and bedsore (47.4%, 63/133) as well as involvement of upper respiratory tract (23.3%, 31/133) and lower respiratory tract (13.5%, 18/133). The drug susceptibility tests showed that Staphylococcus aureus was 100.0% sensitive to vancomycin, linezolid, tigecycline, nitrofurantoin and rifampicin. The resistance rate to penicillin was the highest, 88.0%, followed by crythromycin and clindamycin, 34.6% and 30.1%, respectively. The detection rate of methicillin-resistant Staphylococcus aureus (MRSA) was 23.3% (31/133). Of 31 MRSA strains, 30 carried mecA gene, 6 carried PVL gene, and 5 carried both mecA and PVL genes. Conclusion Staphylococcus aureus infection in hospitalized patients in XuanCheng City Central Hospital primarily occurred in patients from Pulmonary and Critical Care Medicine and Intensive Care Unit. The rate of resistance to penicillin, erythromycin, clindamycin and other antibiotics was high, antibiotics should be rationally prescribed and standardized according to the drug susceptibility test results in clinical management of the infection.

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    TEACHING EXPLORATION
    Promotion and realization of curriculum ideological and political education in the construction of first-class course of Human Parasitology
    JIANG Feng, ZHAO Jin-hong, GU Sheng-li, TANG Xiao-niu, ZHAN Xiao-dong, LIU Ting
    2023, 21 (3):  178-封三.  doi: 10.3969/j.issn.1672-2302.2023.03.013
    Abstract ( 402 )   HTML ( 10 )   PDF (850KB) ( 1117 )  

    With further practice of the concept of curriculum ideological and political education in China, colleges and universities gradually run ideological and political education through the whole process of professional education and teaching in higher learning institutions. This paper analyzes the promoting effect of ideological and political education on the construction of first-class courses in Human Parasitology in combination with the teaching practice by the Department of Medical Parasitology of Wannan Medical College, i.e., enhancing teachers' ideological and political literacy, excavating and summarizing the materials related to the ideological and political education, exploring the teaching methods of curriculum ideology and political education, so as to optimize the teaching effect, and provide practical reference for construction of the first-class course of Human Parasitology teaching.

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