Objective To evaluate the end-term effectiveness following of medium-long-term program for schistosomiasis control in Hunan Province from 2004 to 2014 for evidence to plan controlling measures in following tasks. Methods Comprehensive measures were carried out in implementation of the program, including snail control, chemotherapy for residents and livestock, health education and control of the infectious sources. The end-term effectiveness was evaluated based on the schistosomiasis detection in population and livestock as well as survey on the prevalence status of snails in local area specified in the medium- and long-term program. Results From 2004 to 2014, schistosomiasis detection was given in 7 616 000 person-times, chemotherapy in 5 071 000 person-times, and treatment in 35 700 individuals of advanced schistosomiasis. A total of 1 279 000 cattle were subjected to detection of the schistosome infection, and 1 718 000 cattle to chemotherapy. Snail survey and use of molluscicide covered an area of 885 200 hm2 and 170 200 hm2, respectively. Marshland isolation and farming prohibition in lake district were practiced in area of 129 700 hm2, and 82 000 livestock were eliminated. By 2014, the infection rate in population and cattle was reduced to 0.51% and 0.40%, respectively. The areas with snails within the embankment across the province were greatly reduced, yet the areas with snail presence remained approximately 175 000 hm2. The density for living and infected snails was remarkably declined. By 2015, criteria of transmission control, evaluated as individual administrative village, achieved across the province, where 15 counties reached the criteria of transmission interruption. Conclusion Hunan province has achieved the goal of schistosomiasis control specified in the medium-long-term program, and the effectiveness appears remarkable as a result of comprehensive measures on infection source control basis.
