Abstract:

Objective  To measure the antibody levels of measles and hepatitis B among healthy population in Yongsheng county, and to evaluate the effect of vaccination for scientific evidence to plan following immunization program. Methods  By stratified cluster sampling method, we conducted tests on the measles IgG antibody and anti-HBs with ELISA in healthy population in the administrative areas of Yongsheng country from 2013 through 2015, and analyzed the results with software SPSS(version 19.0). Results  A total of 1294 measles samples and 1097 anti-HBs samples were tested between 2013 and 2015. The positive rate was respective 94.98%(1229/1294) and 60.98%(669/1097), and varied significantly for measles antibody and anti-HBs in different year and administrative towns. The positive rate was the highest in population aged between 10 and 13(96.88%, 155/160) for measles antibody and those aged from 8 to 17 months of years(82.80%, 130/157) for anti-HBs, and the lowest in population aged 18 or over(88.57%, 124/140; 37.93%, 33/87, respectively). Positive rate for measles antibody and anti-HBs was increased with immunity history, and the difference was significant, yet remained no significant difference in genders. Conclusion The immune barrier for measles and hepatitis B has been built in population in Yongsheng county. However, the effect is not so satisfactory. Following tasks should target at improvement of the routine immunization rate and quality as well as strengthening the immunization and full immune coverage.

Key words: Healthy population, Measles antibody, Anti-HBs