寄生虫感染相关的环状RNA研究进展

doi:10.20199/j.issn.1672-2302.2024.04.013

热带病与寄生虫学 ›› 2024, Vol. 22 ›› Issue (4): 252-256.doi: 10.20199/j.issn.1672-2302.2024.04.013

• 综述 • 上一篇

寄生虫感染相关的环状RNA研究进展

彭佩英¹^,²(), 易伶¹^,², 贺平¹^,²()

1.西藏民族大学医学院医学检验技术教研室，陕西咸阳 712082
2.国家民委高原低氧环境与生命健康实验室

收稿日期:2023-12-25 出版日期:2024-08-20 发布日期:2024-08-30
通信作者: 贺平，E-mail: hepingyixue@126.com
作者简介:彭佩英，女，硕士在读，研究方向：旋毛虫致病机制研究。E-mail: ppying163@163.com
基金资助:
国家自然科学基金项目(81860365);陕西省自然科学基础研究计划项目(2023-JC-YB-792);西藏自治区自然科学基金项目(XZ202401ZR0017);西藏民族大学重大项目培育计划项目(18MDZ02)

Progress on the study of circular RNAs related to parasitic infections

PENG Peiying¹^,²(), YI Ling¹^,², HE Ping¹^,²()

1. Department of Medical Laboratory Techniques, Medical College of Xizang Minzu University, Xianyang 712082, Shanxi Province, China
2. High Altitude Hypoxia Environment and Life Health Laboratory of National Ethnic Affairs Commission

Received:2023-12-25 Online:2024-08-20 Published:2024-08-30
Contact: HE Ping, E-mail: hepingyixue@126.com

摘要/Abstract

摘要：

环状RNA（circular RNA, circRNA）是一类特殊的非编码RNA分子，具有转录调控和蛋白质翻译等功能。本文综述了寄生虫感染引起宿主circRNA表达变化，以及寄生虫自身的circRNA在调控虫体发育、繁殖等方面发挥作用的相关研究，为进一步的研究提供参考。

关键词: 环状RNA, 寄生虫, 宿主, 调控作用

Abstract:

Circular RNA (circRNA) is a special kind of non-coding RNA molecule, which has the functions of transcriptional regulation and protein translation. In this review, we summarized the changes of host circRNA expression induced by parasite infection and the role of parasite circRNA in regulating parasite development and reproduction, with an attempt to provide evidences in following research.

Key words: CircRNA, Parasite, Host, Regulatory effect

中图分类号:

彭佩英, 易伶, 贺平. 寄生虫感染相关的环状RNA研究进展[J]. 热带病与寄生虫学, 2024, 22(4): 252-256.

PENG Peiying, YI Ling, HE Ping. Progress on the study of circular RNAs related to parasitic infections[J]. Journal of Tropical Diseases and Parasitology, 2024, 22(4): 252-256.

参考文献 33

[1]	Sanger HL, Klotz G, Riesner D, et al. Viroids are single-stranded covalently closed circular RNA molecules existing as highly base-paired rod-like structures[J]. Proc Natl Acad Sci USA, 1976, 73(11):3852-3856 doi: 10.1073/pnas.73.11.3852 pmid: 1069269
[2]	Cocquerelle C, Mascrez B, Hétuin D, et al. Mis-splicing yields circular RNA molecules[J]. FASEB J, 1993, 7(1):155-160. doi: 10.1096/fasebj.7.1.7678559 pmid: 7678559
[3]	Khorsandi K, Esfahani H, Abrahamse H. Characteristics of circRNA and its approach as diagnostic tool in melanoma[J]. Expert Rev Mol Diagn, 2021, 21(10):1079-1094.
[4]	Huang GQ, Liang M, Liu HY, et al. CircRNA hsa_circRNA_104348 promotes hepatocellular carcinoma progression through modulating miR-187-3p/RTKN2 axis and activating Wnt/β-catenin pathway[J]. Cell Death Dis, 2020, 11(12):1065. doi: 10.1038/s41419-020-03276-1 pmid: 33311442
[5]	Wang SS, Chen D, He JJ, et al. Fasciola gigantica-derived excretory-secretory products alter the expression of mRNAs, miRNAs, lncRNAs, and circRNAs involved in the immune response and metabolism in goat peripheral blood mononuclear cells[J]. Front Immunol, 2021,12:653755.
[6]	Ali SA, Peffers MJ, Ormseth MJ, et al. The non-coding RNA interactome in joint health and disease[J]. Nat Rev Rheumatol, 2021, 17(11):692-705. doi: 10.1038/s41584-021-00687-y pmid: 34588660
[7]	尹艳玲. 宿主环状RNA ciRS-7靶向miRNAs影响微小隐孢子虫在HCT-8细胞中增殖的机制[D]. 杨凌: 西北农林科技大学, 2022.
[8]	Giri BR, Fang CT, Cheng GF. Genome-wide identification of circular RNAs in adult Schistosoma japonicum[J]. Int J Parasitol, 2022, 52(9):629-636.
[9]	Li Z, Lu J. CircRNAs in osteoarthritis: research status and prospect[J]. Front Genet, 2023,14:1173812.
[10]	Klein P, Kleinová T, Volek Z, et al. Effect of Cryptosporidium parvum infection on the absorptive capacity and paracellular permeability of the small intestine in neonatal calves[J]. Vet Parasitol, 2008, 152(1/2):53-59.
[11]	Yin YL, Liu TL, Yao Q, et al. Circular RNA ciRS-7 affects the propagation of Cryptosporidium parvum in HCT-8 cells by sponging miR-1270 to activate the NF-κB signaling pathway[J]. Parasit Vectors, 2021, 14(1):238.
[12]	Yin YL, Yang X, Huang S, et al. Circular RNA ciRS-7 affects the propagation of Cryptosporidium parvum in HCT-8 cells via regulating miR-135a-5p/stat1 axis[J]. Acta Trop, 2023,243:106927.
[13]	Sun LL, Li JF, Xie FJ, et al. Whole transcriptome analysis of HCT-8 cells infected by Cryptosporidium parvum[J]. Parasit Vectors, 2022, 15(1):441.
[14]	Ren GJ, Fan XC, Liu TL, et al. Genome-wide analysis of differentially expressed profiles of mRNAs, lncRNAs and circRNAs during Cryptosporidium baileyi infection[J]. BMC Genomics, 2018, 19(1):356.
[15]	任冠静. 贝氏隐孢子虫感染雏鸡气管的lncRNA与circRNA的表达谱研究[D]. 杨凌: 西北农林科技大学, 2018.
[16]	Zhou CX, Ai K, Huang CQ, et al. miRNA and circRNA expression patterns in mouse brain during toxoplasmosis development[J]. BMC Genomics, 2020, 21(1):46.
[17]	Zou Y, Meng JX, Wei XY, et al. CircRNA and miRNA expression analysis in livers of mice with Toxoplasma gondii infection[J]. Front Cell Infect Microbiol, 2022,12:1037586.
[18]	巴合提·卡力甫. 环状RNA在肝包虫外囊组织中表达谱鉴定及初步机制研究[D]. 乌鲁木齐: 新疆医科大学, 2021.
[19]	Kalifu B, Maitiseyiti A, Ge XH, et al. Expression profile of circular RNAs in cystic echinococcosis pericystic tissue[J]. J Clin Lab Anal, 2021, 35(3):e23687.
[20]	李秀荣, 李立, 闫鸿斌, 等. 基于高通量测序的多房棘球蚴感染小鼠肝组织中差异circRNA的生物信息学分析[J]. 中国兽医科学, 2020, 50(4):437-443.
[21]	李秀荣. 多房棘球蚴感染小鼠肝脏差异表达circRNA筛选及其ceRNA网络构建[D]. 北京: 中国农业科学院, 2020.
[22]	Liu TL, Wang LQ, Li H, et al. circRNA expression pattern and circRNA-miRNA-mRNA network in HCs, HSCs, and KCs of murine liver after Echinococcus multilocularis infection[J]. Front Vet Sci, 2022,9:825307.
[23]	Özdemir S, Aksungur N, Altundaş N, et al. Genome-wide profiling of the expression of serum derived exosomal circRNAs in patients with hepatic alveolar echinococcosis[J]. Gene, 2022,814:146161.
[24]	邹扬, 郑文斌, 张金鹏, 等. 犬弓首蛔虫感染比格犬不同阶段肝circRNAs表达模式的分析[J]. 畜牧兽医学报, 2021, 52(12):3524-3534. doi: 10.11843/j.issn.0366-6964.2021.012.019
[25]	赵宇豪. 青蒿琥酯作用日本血吸虫童虫后mRNA及长链非编码RNA的差异表达谱研究[D]. 杭州: 浙江省医学科学院, 2020.
[26]	刘华熳, Bikash Giri, 方传涛, 等. 日本血吸虫m6A修饰的性别相关circRNA鉴定[J]. 中国寄生虫学与寄生虫病杂志, 2023, 41(5):552-558 doi: 10.12140/j.issn.1000-7423.2023.05.005
[27]	Zhang XF, Gong WC, Cao SK, et al. Comprehensive analysis of non-coding RNA profiles of exosome-like vesicles from the protoscoleces and hydatid cyst fluid of Echinococcus granulosus[J]. Front Cell Infect Microbiol, 2020,10:316.
[28]	Zhou CX, Zhang Y, Wu SM, et al. Genome-wide identification of CircRNAs of infective larvae and adult worms of parasitic nematode, Haemonchus contortus[J]. Front Cell Infect Microbiol, 2021,11:764089.
[29]	Wang PL, Bao Y, Yee MC, et al. Circular RNA is expressed across the eukaryotic tree of life[J]. PLoS One, 2014, 9(6):e90859.
[30]	Broadbent KM, Broadbent JC, Ribacke U, et al. Strand-specific RNA sequencing in Plasmodium falciparum malaria identifies developmentally regulated long non-coding RNA and circular RNA[J]. BMC Genomics, 2015, 16(1):454.
[31]	Minkler SJ, Loghry-Jansen HJ, Sondjaja NA, et al. Expression and secretion of circular RNAs in the parasitic nematode, Ascaris suum[J]. Front Genet, 2022,13:884052.
[32]	López-Luis MÁ, Padrón-Manrique CJC, García-Lerena JA, et al. In silico identification and characterization of circRNAs as potential virulence-related miRNA/siRNA sponges from Entamoeba histolytica and encystment-related circRNAs from Entamoeba invadens[J]. Noncoding RNA, 2022, 8(5):65.
[33]	Kristensen LS, Andersen MS, Stagsted LVW, et al. The biogenesis,biology and characterization of circular RNAs[J]. Nat Rev Genet, 2019, 20(11):675-691. doi: 10.1038/s41576-019-0158-7 pmid: 31395983

寄生虫感染相关的环状RNA研究进展

Progress on the study of circular RNAs related to parasitic infections

RichHTML

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献 33

相关文章 15

编辑推荐

Metrics

本文评价

[1]	王俊锋, 吴昊, 李美娜, 赵庆龙. 2018—2023年吉林省肾综合征出血热流行特征及宿主动物监测分析[J]. 热带病与寄生虫学, 2024, 22(3): 133-139.
[2]	田育文, 沈纪川, 高飞, 马涛, 胡泉博, 所佳宁, 袁爽. 2018—2023年黑龙江省肾综合征出血热流行趋势分析[J]. 热带病与寄生虫学, 2024, 22(3): 147-151.
[3]	戴艳妮, 李青, 储修杰, 袁媛, 孙永, 龚磊. 2019—2023年安徽省肾综合征出血热流行特征与宿主动物监测分析[J]. 热带病与寄生虫学, 2024, 22(3): 152-156.
[4]	向柯华, 雷明盛, 赵蓓, 朱明新, 李晋, 粟仲锐. 胸肺型合并脑型并殖吸虫病1例[J]. 热带病与寄生虫学, 2024, 22(1): 57-60.
[5]	熊彦红, 曹建平, 郑彬. 寄生虫病原实验室生物安全风险评估规范化培训方案建立及探讨[J]. 热带病与寄生虫学, 2023, 21(5): 291-294.
[6]	陈琳, 曹淳力. 新形势下我国寄生虫病健康教育和科普工作的挑战与展望[J]. 热带病与寄生虫学, 2023, 21(4): 181-185.
[7]	赵陆源, 周长海, 诸廷俊, 黄继磊, 刘剑峰, 陈颖丹, 王强, 李石柱, 周晓农, 钱门宝. 2021年全国寄生虫病健康教育作品评比结果分析[J]. 热带病与寄生虫学, 2023, 21(4): 238-242.
[8]	邵伟, 陶芸, 周倩倩, 刘淼, 计永胜, 沈际佳. 翻转课堂在人体寄生虫学课程线上教学中的应用[J]. 热带病与寄生虫学, 2023, 21(4): 243-封三.
[9]	蒋峰, 赵金红, 谷生丽, 唐小牛, 湛孝东, 刘婷. 课程思政在人体寄生虫学一流课程建设中的推动作用和实现路径[J]. 热带病与寄生虫学, 2023, 21(3): 178-封三.
[10]	蔡娇娇, 向尧, 许静茹, 谭妍, 周杨, 李志峰. 2021年重庆市寄生虫病防治技术竞赛成绩分析[J]. 热带病与寄生虫学, 2023, 21(2): 112-115.
[11]	田一妮, 勒斌, 张逸龙, 张冬梅. 某医学院校本科生医学寄生虫学课程教学思考——以食源性寄生虫病为例[J]. 热带病与寄生虫学, 2023, 21(2): 116-119.
[12]	邓胜群, 吴心瑜, 杜忆南, 任翠平, 张超, 刘淼. “钉钉”课堂在来华留学生人体寄生虫学课程教学中的实践与思考[J]. 热带病与寄生虫学, 2022, 20(6): 342-345.
[13]	朱维, 高雷明, 刘海霞, 米荣升, 李宗杰. 寄生虫对肠道菌群和宿主免疫功能影响的研究进展[J]. 热带病与寄生虫学, 2022, 20(6): 352-356.
[14]	蔡娇娇, 许静茹, 李志峰, 谭妍, 向尧. 2016—2021年重庆市寄生虫病防治技术竞赛成绩分析[J]. 热带病与寄生虫学, 2022, 20(5): 264-269.
[15]	赵金红, 唐小牛, 郭俊杰, 刘婷. 人体寄生虫学课程思政案例教学的实践与思考[J]. 热带病与寄生虫学, 2022, 20(5): 276-280.