Journal of Tropical Diseases and Parasitology ›› 2024, Vol. 22 ›› Issue (3): 140-146.doi: 10.3969/j.issn.1672-2302.2024.03.003

• TOPICS FOR HEMORRHAGIC FEVER WITH RENAL SYNDROME • Previous Articles     Next Articles

Investigation on the endemic status and risk factors of hemorrhagic fever with renal syndrome in Gansu Province from 2017 to 2022

WANG Ruiying1(), DING Fan2, YAO Jinxi1, WU Jialong1, WANG Yun1, WEI Kongfu1()   

  1. 1. Gansu Provincial Center for Disease Control and Prevention, Lanzhou 730000, Gansu Province, China
    2. Chinese Center for Disease Control and Prevention
  • Received:2023-12-11 Online:2024-06-20 Published:2024-06-28
  • Contact: WEI Kongfu, E-mail: weikf2006@126.com

Abstract:

Objective To analyze the epidemiological patterns of hemorrhagic fever with renal syndrome (HFRS) in Gansu Province, and investigate the primary risk factors affecting the incidence of HFRS among residents for reference in formulating targeted strategies and measures for prevention and control of this infection. Methods The relevant information of HFRS cases reported in Gansu Province from 2017 to 2022 was collected through the China Disease Prevention and Control Information System, and descriptive analysis was conducted on the temporal, regional and demographic distribution of HFRS cases. Furthermore, a case-control study was carried out on HFRS cases reported in Min County, Dingxi City from 2020 to 2022 to analyze the primary risk factors affecting the incidence of this acute zoonotic condition. Results In total, 747 cases of HFRS were reported in Gansu Province from 2017 to 2022, with an average annual incidence of 0.50 per 100 000 population. The highest incidence occurred in 2019, reaching 1.28 per 100 000 population. The reported cases were 469 (62.78%) for males, and 278 (37.22%) for females, with an average annual reported incidence of 0.61/100 000 and 0.38/100 000 population, respectively for each gender. In different age groups, the number of reported cases was the largest in population aged 45-59 years (296 cases, 39.63%), followed by those aged 30-44 years (184 cases, 24.63%). Farmers were the most involved in HFRS (487 cases, 65.19%), followed by herdsmen (133 cases, 17.81%). The incidence of HFRS was mainly concentrated in October to December (569 cases, 76.17%), with the peak occurring in November (262 cases, 35.07%). The reported cases were mainly in Xiahe County, Min County and Lingtai County, with a cumulative number of reported cases being 571 (76.44%). The results of the case-control study showed that the potential risks for HFRS were associated with absence of vaccination against HFRS (OR=5.99), presence of rat cavity in the house (OR=3.99), no wearing a mask when digging and organizing herbs (OR=10.45), intake of food contaminated by rodents (OR=5.49), contact with rodents or rodent feces (OR=11.64), and drinking unboiled water (OR=6.97). Conclusion From 2017 to 2022, the incidence of HFRS in Gansu Province showed a trend of first increasing and then decreasing, with a concentrated period and area of high incidence. For the areas of high incidence, preventive vaccination, health education and improvement of the living environment should be carried out in due course to strengthen residents' awareness of protection and guide them to develop better dietary and hygienic habits, so as to reduce the risk of the infection.

Key words: Hemorrhagic fever with renal syndrome, Epidemiological characteristics, Risk factors, Case-control studies, Gansu Province

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