热带病与寄生虫学 ›› 2026, Vol. 24 ›› Issue (2): 115-123.

• 病例报道 • 上一篇    下一篇

布鲁氏菌感染引起髂动脉瘤及腹主动脉夹层动脉瘤1例并文献复习

万传珍1,朱德全2,董学军1,吴翠萍1   

  1. 1. 山东第二医科大学附属益都中心医院,山东潍坊261000;2. 湖北医药学院附属十堰市太和医院

  • 收稿日期:2025-11-25 出版日期:2026-04-20 发布日期:2026-05-29
  • 通信作者: 吴翠萍,E-mail: 1379014132@qq.com
  • 作者简介:万传珍,女,硕士在读,研究方向:传染病学。E-mail: 2447592995 @qq.com

Bilateral iliac artery aneurysms with abdominal aortic dissecting aneurysm caused by Brucella infection: Report of one case with literature review

WAN Chuanzhen1, ZHU Dequan2, DONG Xuejun1, WU Cuiping1   

  1. 1. Yidu Central Hospital, Shandong Second Medical University, Weifang 261000, Shandong Province, China;
    2. Taihe Hospital of Shiyan City, Hubei University of Medicine
  • Received:2025-11-25 Online:2026-04-20 Published:2026-05-29

摘要:

摘要:本文报道了1例布鲁氏菌感染引起的髂动脉瘤及腹主动脉夹层动脉瘤病例。患者因反复发热、下腹痛就诊,腹部增强CT提示腹主动脉假性动脉瘤并双侧髂动脉病变,先后接受腹主动脉腔内隔绝术(endovascular aneurysm repair, EVAR)及髂动脉支架植入术,经围手术期预防性抗感染治疗后,患者体温短暂恢复正常,但出院后再次出现发热及腹痛。进一步追问流行病学史发现患者为羊养殖户,布鲁氏菌虎红平板凝集试验(rose bengal plate test, RBPT)呈阳性,试管凝集试验(serum agglutination test, SAT)滴度为1∶200,血培养检出布鲁氏菌(羊种3型),最终确诊为布鲁氏菌病相关感染性动脉瘤。经多西环素、利福平及左氧氟沙星三联抗生素治疗后,患者病情好转出院,院外继续口服多西环素及利福平治疗,随访良好。本文对该病例资料进行回顾分析并对相关文献进行检索与复习,归纳该病的临床特征、诊断及治疗要点,总结诊疗经验,以提高临床对该病的认识。

关键词: 布鲁氏菌, 感染性动脉瘤, 诊断, 治疗

Abstract:

Abstract: This article reports one case of iliac artery aneurysm and abdominal aortic dissecting aneurysm secondary to Brucella infection. The patient visited the hospital due to recurrent fever and lower abdominal pain. Contrast-enhanced computed tomography revealed an abdominal aortic pseudoaneurysm with bilateral iliac artery involvement. The patient subsequently underwent endovascular aneurysm repair (EVAR) and iliac artery stenting.  Following perioperative prophylactic antimicrobial therapy, the patient’s body temperature temporarily recovered to normal, yet fever and abdominal pain recurred after discharge. Further epidemiological inquiry demonstrated that the patient was a sheep farmer. The Rose Bengal plate test (RBPT) was positive, with a titer of 1∶200 by the serum agglutination test (SAT). The blood culture detected Brucella melitensis biovar 3, thereby confirming the diagnosis of brucellosis-associated infected aneurysm. After triple-antibiotic therapy with doxycycline, rifampicin, and levofloxacin, the patient improved clinically and was discharged. The patient then continued outpatient oral treatment with doxycycline and rifampicin, and the outcome was favorable during follow-up. The clinical data of this case were retrospectively analyzed, with related literatures reviewed to summarize the clinical characteristics, diagnostic approaches, and therapeutic strategies of this condition, with an attempt to enhance clinical understanding of the disease.

Key words: Brucella, Infected aneurysm, Diagnosis, Therapy