Objective　To estimate the disease burden of common intestinal parasitic infection in Yunnan Province from 2015 to 2019 for evidence to optimize allocation of resources in prevention and control of this prevalence. Methods　Common intestinal parasitic infection and gender standardized infection rates from 2015 to 2019 as well as the disease burden were computed using the formula of disability-adjusted life years(DALYs)based on the surveillance data from Yunnan Institute of Parasitic Diseases. Results　Common intestinal parasitic infection rate between 2015 and 2019 was 10. 47%. The parasites involved in the infection consisted of hookworm,roundworm and whipworm,with an infection rate of 3. 98%, 3. 00% and 3. 49%,respectively. Males had lower infection than females(9. 83% vs. 11. 07%),with difference between genders(χ 2 =26. 889,P<0. 05). The common intestinal parasitic infection,including hookworm,roundworm and whipworm, tended to decrease from 2015 to 2019 in Yunnan(χ 2 = 1 903. 447,460. 915,754. 366 and 790. 847,respectively,all P<0. 05). The gender standardized infection rate was also yearly decreased from 24. 99% to 5. 71%( r_s =-1,P<0. 05). Common intestinal parasitic infection rate by DALYs was 11. 483 per year,in which DALYs was 5. 249 per year for males,and 6. 234 per year for females between 2015 and 2019. DALYs was the highest in 2016,with 17. 218 per year. The rate for DALYs by common intestinal parasitic infection,including hookworm,roundworm and whipworm,tended to decrease (r_s =-1,-0. 9,-0. 9 and-1,all P<0. 05),yet varied among different age groups,with the highest rate of DALYs in population aged between 5 and 14 years(8. 546 per 1 000 population). Conclusion　Although the burden of common intestinal parasite diseases in Yunnan Province is decreasing annually,yet it is still necessary to strengthen the prevention and control in children in order to further reduce the disease burden of common intestinal parasites.