Abstract: Objective To understand the epidemic trend of schistosomiasis in Hefei through systematically analyzing the endemic status of schistosomiasis in national surveillance sites from 2016 to 2020 for scientific evidence to develop prevention and control strategies for schistosomiasis in Hefei. Methods Monitoring data were collected from the national surveillance sites within Hefei area from 2016 throughout 2020,and analyzed using descriptive statistics. Results Overall,the snail situation in Hefei area remained stable between 2016 and 2020,though fluctuation occurred in small range. Snail reemerged in an area of 0. 50 hm² in 2019,yet no infected snails were found by microscopic examination. Positive rate of blood test for  Schistosoma japonicum in population was decreased to zero from the maximal 0. 27% in 2018. There was no location infection in population or in livestock in the past five years. Conclusion Comprehensive strategies focusing on control of the transmission sources were uninterruptedly implemented in Hefei area from 2016 to 2020,which resulted in schistosomiasis infection in relatively lower scale in history throughout the city,though the risks of local transmission still exist in certain areas. The following efforts should be targeted at those areas by continuously strengthening the surveillance.

Key words: Schistosomiasis, Endemic situation, Surveillance, Hefei City