Abstract: Objective To identify the high-risk environments of Schistosoma japonicum infection in the key water body in Wuhan area for reducing the risks of schistosomiasis. Methods The key water areas with most prevalence of Schistosoma japonicum in Yangtze River within the section of Wuhan City were selected,including Fuhe-Lunhe river system,Dongjing River-Tongshun River system and Jinshui River system. Sentinel mice were used to monitor the risks of Schistosoma japonicum infection. Results From 2017 to 2019,a total of 38 surveillance and forecast sites were detected in 21 administrative villages of 8 districts. Of the 760 sentinel mice placed,742 were recovered,with a recovery rate of 97. 63%. No positive infection and no adult worms were found in the 742 sentinel mice dissected. The infection rate of sentinel mouse was zero. Conclusion The infectivity of Schistosoma japonicum remains relative lower in the key water body in Wuhan area.

Key words: Schistosomiasis, Sentinel mice, Water infectivity, Wuhan City