Abstract: Objective To understand the status of recessive infection of enterovirus and infectious diarrhea virus in population in Yantian district of Shenzhen City for scientific evidence to formulate prevention and control measures. Methods In 2020,one community was randomly selected by clustering method as survey site from each of the four blocks (Haishan,Shatoujiao,Yantian and Meisha) under administration of Yantian District. Fecal samples were collected from local residents, and detected with real-time fluorescence quantitative PCR for norovirus,zavirus,rotavirus,star virus,intestinal adenovirus, intestinal universal type,enterovirus 71 (EV 71) and coxsackievirus A16 (CV-A16). Results Totally,813 aliquots of fecal samples were collected and tested,in which no zavirus,rotavirus,star virus,intestinal adenovirus,EV 71 and CA16 were detected. Universal type of human entrovirus,which was associated with oral polio vaccine,was found in 2 children,with a positive rate of 0. 25%. Norovirus(genogroup Ⅱ) was detected in 4 cases,with a positive rate of 0. 49%. Two out of the 4 norovirus positive samples were successfully sequenced,which were confirmed as genotype GⅡ. 2-GⅡ. P16 and GⅡ. 17-G Ⅱ. P17,and had higher homology with the strains prevalent in China in recent years. Conclusion Recessive infection of norovirus exists in the population in Yantian district of Shenzhen City. The findings suggest that surveillance should be strengthened key population and areas. 

Key words: Enterovirus, Norovirus, Recessive infect