Abstract: Objective To understand the status of Toxoplasma gondii(T. gondii) infection in patients infected with HIV /AIDS in Fuyang city of Anhui Province,and investigate the effect of co-infection on the count of CD4+T lymphocytes for evidence in prevention and control of T. gondii  infection in patients infected with HIV / AIDS. Methods The newly reported patients infected with HIV / AIDS without medication were included from January 2020 to March 2021 in Fuyang city. Enzyme-linked immunosorbent assay (ELISA) was performed to measure the serum IgG antibody against T. gondii ,and the levels of CD4+T lymphocytes in all subjects. Results Totally,449 HIV / AIDS infected patients(348 males,75 females) underwent the survey. Thirty-six patients were unknown genders,and the patients aged from 20 to 60 years old. IgG antibody positive for T. gondii  was detected in 5 patients(1. 11%). CD4+T lymphocyte count was from the lowest 1 cell / μL to up to 1 616 cells / μL in patients with negative IgG antibody against T. gondii. The median ( interquartile range) was 287(170, 439) cells / μL. CD4+T lymphocyte count ranged minimally from 43 cells / μL to maximally 325 cells / μL in HIV / AIDS infected patients with IgG antibody positive for T. gondii ,with median ( interquartile range) of 139(86,237) cells / μL. The difference was insignificant in patients with negative or positive IgG T. gondii  antibody ( Z= -1. 749,P>0. 05). Conclusion T. gondii prevalence seems lower in HIV / AIDS infected patients in Fuyang city,and the relationship between CD4+T lymphocyte count and T. gondii  infection needs further investigating in such victims.

Key words: HIV / AIDS, Toxoplasma gondii, Fuyang City