Abstract: Epidemiology is a basic discipline in preventive medicine, which possesses strong theoretical and practical nature. In current stage in prevention and control of COVID-19 epidemic, how to improve the practical ability of students in their competency in disease prevention and control services represents an urgent problem in the teaching reform of epidemiology course. Integrated online and offline instruction based on small private online course(SPOC) is a newly emerged teaching mode, and widely and tentatively applied to class teaching in many higher learning institutions. This paper aims at discussing the necessity of implementing mixed teaching for epidemiology, the process of instruction by SPOC mode and reflections in the teaching based on the property of epidemiology course and teaching status, with an attempt to provide reference for the teaching reform of epidemiology.

Key words: Small private online course(SPOC), Mixed teaching, Epidemiology, Teaching practice