Abstract: Japanese encephalitis is a zoonosis caused by Japanese encephalitis virus. It is mainly transmitted through bites of mosquitoes in natural environment,causing diseases such as injury of human central nervous system and disorders in pig breeding as well as leading to serious threat to the public health and safety. Currently,the dominant genotype of Japanese encephalitis virus is shifting from GⅢ to GIⅠ because of the adaptability difference of the virus in waterfowl hosts. Transformation of the dominant Japanese encephalitis virus genotypes and extension of epidemic scope have brought new challenges to disease prevention and control. This paper reviews the research progress in the shifting trend of dominant genotype of Japanese encephalitis virus and its control strategies in China.

Key words: Japanese encephalitis, Japanese encephalitis virus, Risk analysis, Genotype shift, Control strategies