Abstract: Objective To investigate the related risk factors for hepatic alveolar echinococcosis complicated with lung alveolar echinococcosis. Methods General data,laboratory and imaging findings were collected from the patients of hepatic alveolar echinococcosis complicated with lung alveolar echinococcosis (combined group) and those of hepatic alveolar echinococcosis without lung alveolar echinococcosis (control group),treated in the Department of Hepatopancreatobiliary Surgery of Affiliated Hospital of Qinghai University between October 2017 and April 2019. Then the related factors affecting occurrence of hepatic alveolar echinococcosis concomitant with lung alveolar echinococcosis were analyzed. Results Forty-nine cases of hepatic alveolar echinococcosis complicated with lung alveolar echinococcosis,and 55 cases of hepatic alveolar echinococcosis without lung alveolar echinococcosis were included. There was no significant difference in gender and age between groups( χ2 = 2. 164,2. 780,respectively,both P>0. 05). Univariate regression analysis indicated that HBeAg,infiltration of the intrahepatic lesions into posterior-inferior vena cava,hepatic arteries,hepatic veins and portal veins were the influencing factors for hepatic alveolar echinococcosis concomitant with lung alveolar echinococcosis. Multivariate logistic regression analysis showed that invasion of intrahepatic lesions into posterior-inferior vena cava and hepatic veins were independent risk factors for hepatic alveolar echinococcosis complicated with lung alveolar echinococcosis. Conclusion For patients of alveolar echinococcosis with ambiguous lung lesions,sound judgment can be made in accordance with preoperative imaging findings of intrahepatic lesions and lung lesions,with implementation of targeted intervention,so as to maximize the clinical benefits for such patients.

Key words: Hepatic alveolar echinococcosis, Lung alveolar echinococcosis, Imaging diagnosis, Vascular invasion, Risk factors