Journal of Tropical Diseases and Parasitology

Journal of Tropical Diseases and Parasitology ›› 2021, Vol. 19 ›› Issue (1): 47-51.

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AMPK signaling pathway and its research progress in infectious disease

YAN Ming-zhi1 2 ,ZHAO Jun3, LIU Hui1 ,BI Xiao-juan1 ,LÜ Guo-dong1 2   

  1. 1 State Key Laboratory of Pathogenesis Prevention and Treatment of Central Asian High Incidence Diseases Clinical Medical Research Institute The First Affiliated Hospital of Xinjiang Medical University ,Urumqi 830054 ,Xinjiang Uygur Autonomous Region ,China;2 College of Pharmacy Xinjiang Medical University;3 Department of Clinical Pharmacy The First Affiliated Hospital of Xinjiang Medical University
  • Online:2021-02-20 Published:2021-02-04

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Abstract: AMP-activated protein kinase (AMPK),an AMP-dependent protein kinase responsible for regulating the synthesis and catabolism of cellular energy,is a key regulator for cell growth,reproduction and autophagy.AMPK and its signaling pathway play an important role in viral,bacterial and parasitic infections and are expected to be a new drug target.In this paper,we reviewed the recent research on AMPK signaling pathway in infectious diseases.

Key words: AMPK signaling pathway, Energy metabolism, Infectious diseases , Pathogens , Drug target

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