Abstract:

Objective To detect the indexes of blood coagulation in patients with advanced schistosomiasis (AS) compared with chronic schistosomiasis (CS), probe its coagulation mechanism, monitor the bleeding tendency timely and provide basis for clinical treatment. Methods Prothrombin time (PT), activated partial thromboplastin time (APTT) and thrombin time (TT) of 37 patients with AS and 80 with CS were detected by Rayto RT- 2204C coagulation analyzer. Results PT, APTT and TT of patients with AS were obvious higher than patients with CS（P<0.01）.Conclusion The blood coagulation function of patients with AS is obvious abnormal. Detecting the indexes of blood coagulation is significant to monitoring the bleeding tendency and instructing the clinical medication for patients with AS.

Key words: Advanced schistosomiasis, Blood coagulation, PT, APTT, Thrombin time