我国手足口病病原谱变化趋势及防控对策

doi:10.20199/j.issn.1672-2302.2025.04.001

摘要/Abstract

摘要：

手足口病是由多种肠道病毒引起的儿童常见传染病，在西太平洋地区流行较为严重，是全球重要的公共卫生问题。近年来，随着手足口病病原谱改变，我国手足口病的防控工作面临着新的挑战。本文介绍了国内外手足口病病原谱的演变趋势，分析了我国手足口病病原谱的变化特点及其对临床诊疗和防控的影响，并重点从加强病原监测、加快多价疫苗研发、落实非药物干预措施等方面提出了对策和建议，以期为新形势下手足口病防控工作提供参考。

关键词: 手足口病, 病原谱, 血清型, 防控对策

Abstract:

Hand, foot and mouth disease (HFMD) is a common infection in children caused by various enteroviruses. It is more prevalent in the Western Pacific Region, and remains significant global public health concerns. In recent years, the prevention and control of HFMD in China is facing new challenges with change of the pathogen spectrum of HFMD. This paper reviewed the evolutionary trends of HFMD pathogen spectrum at home and abroad, and detailed the changing characteristics of HFMD pathogen spectrum in China and its impact on clinical diagnosis, treatment, and disease control. Besides, corresponding countermeasure and proposals were put forward from targeted aspects as strengthening the pathogen monitoring, accelerating the research and development of multivalent vaccines, and implementing non-pharmaceutical intervention measures, with an attempt to provide references for the prevention and control of HFMD in the new situation.

Key words: Hand, foot and mouth disease, Pathogen spectrum, Serotype, Prevention and control strategies

中图分类号:

R181.3

张志杰, 常昭瑞. 我国手足口病病原谱变化趋势及防控对策[J]. 热带病与寄生虫学, 2025, 23(4): 195-198,215.

ZHANG Zhijie, CHANG Zhaorui. Evolving trends in the pathogen spectrum of hand, foot and mouth disease in China and strategies for prevention and control[J]. Journal of Tropical Diseases and Parasitology, 2025, 23(4): 195-198,215.

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