热带病与寄生虫学

热带病与寄生虫学 ›› 2014, Vol. 12 ›› Issue (3): 161-.doi: 10.3969/j.issn.1672-2302.2014.03.012

• 论著 • 上一篇    下一篇

一起鼠型斑疹伤寒爆发疫情中患者血清恙虫病抗体检测

亚红祥,张海林   

  1. 671000 云南大理市, 云南省地方病防治所/云南省病毒立克次体研究中心/云南省自然疫源性疾病重点实验室
  • 出版日期:2014-09-10 发布日期:2014-10-17

Detection of antibody against scrub typhus in sera from patients in an outbreak of murine typhus

Ya Hongxiang, Zhang Hailin   

  1. Yunnan key laboratory of antural focus disease, Yunnan center of virus and rickettsia research,Yunnan Institute of Endemic Diseases Control and Prevention, Dali 671000, China
  • Online:2014-09-10 Published:2014-10-17

被引次数

6

摘要： 目的 筛查一起鼠型斑疹伤寒爆发疫情患者血清中恙虫病抗体。方法 用间接免疫荧光法对20 份爆发疫情病人血清进行鼠型斑疹伤寒和恙虫病IgG 抗体检测。结果 20 例患者中，鼠型斑疹伤寒抗体阳性13 例，阳性率65%；恙虫病抗体阳性2 例（同时鼠型斑疹伤寒抗体阳性），阳性率10%。结论 该起鼠型斑疹伤寒爆发疫情患者中存在恙虫病感染，临床上应加强对鼠型斑疹伤寒与恙虫病的诊断与鉴别诊断。

关键词: 恙虫病, 鼠型斑疹伤寒, IgG 抗体, IFA 检测

Abstract:

Objective To detect the antibody against scrub typhus in sera from patients in an outbreak of murine typhus. Methods The IgG against murine typhus and scrub typhus from 20 sera samples collected from patients in an outbreak were tested by indirect immunofluoresence assay (IFA). Results For the 20 cases, 13 cases were positive with IgG antibody against murine typhus (accounting for 65%), 2 cases were positive with IgG antibody against scrub typhus and murine typhus (accounting for 10%). Conclusion There were patients infected with chigger simultaneously in this outbreak of murine typhus and it was necessary for medical institutions to enhance the diagnosis and differential diagnosis forscrub typhus and murine typhus.

Key words: Scrub typhus, Murine typhus, IgG antibody, IFA test