Abstract: Objective To analyze the status of registered patients with advanced schistosomiasis in Tongcheng City by the end of 2020 for scientific evidences to develop treatment measures for this group of patients. Methods Epidemiological investigation and analysis were performed on the existing cases of advanced schistosomiasis in Tongchen City, registered by the end of 2020 in the Parasite Control Information Management Platform of Chinese Center for Disease Control and Prevention. All cases were reviewed and identified by local experts, and underwent evaluation for the self-care ability. Results Totally, 152 cases of advanced schistosomiasis were registered in Tongchen City by the end of 2020. Eleven patients were identified in active screening between 2018 and 2020, which accounted for 7.24% of the totally reported cases. Seventy-three were males, and 79 females. The age ranged from 35 to 95 years, with an average of 74.5 years. The 152 cases were distributed in 13 towns/communitis, including Fangang, Xindu, Xizihu etc. The clinical classification was primarily involved in ascites (n=147) and splenomegaly(n=5). No cases of colon thickening and dwarf were found. The average diagnosis was 15 years (ranging from 1 year to 61 years) in the current 152 cases. All patients underwent treatment on hospitalization basis each year, and the treatment ranged from 16 sessions to one secession, with an average of treatment sessions by 10. Of the 152 patients, 128 were complicated with primary conditions. Among the 152 patients with advanced schistosomiasis, 143 were in self-care ability at grade 1; 4 at grade 2; 5 at grade 3. Conclusion The advanced schistosomiasis patients in Tongcheng City tends to be aged, and most of them are complicated with primary conditions. The findings suggest integrated treatment measures should be taken and strengthened in order to improve the quality of life for those patients. 

Key words: Advanced schistosomiasis, Quality of survival, Tongchen City