Abstract: Objective To retrospectively analyze the clinical characteristics of dengue in different age group in Ruili city from 2017 to 2018 for evidence for local health administrations to plan effective measures in diagnosis and treatment of this infection.Methods A total of 571 cases of dengue treated in Ruili People’s Hospital from 2017 to 2018 were divided into minor group(1~18 years),adult group (>18~60 years) and elderly group (>60 years).Analysis was performed regarding the clinical symptoms,signs and laboratory findings in the three groups.Results Of the 571 cases,117 were minors,422 adults and 32 elderly.The clinical symptoms were dominated by fever (97.0%),fatigue( 84.2%),poor appetite(82.3%),headache(76.0%) and systemic muscle soreness(74.1%),and headache, systemic muscle soreness,fatigue and poor appetite were more common in adult group than in minor group.Fever was few seen in elderly group.Abnormal biochemical indicators were primarily associated with decreased WBC (52.4%) and increased AST(53.4%).Minors had lower incidence of abnormal blood glucose and electrolyte,yet had elevated levels of alkaline phosphatase and total bilirubin compared to adults and the elderly.Incidence of myo-cardial damage was the highest in minors group,and decreased WBC was the lowest in adult group.Elderly patients had the highest incidence of PLT decrease and damage of renal function.Conclusion The patients with dengue virus infection treated in Ruili People's Hospital of Yunnan Province are mainly adults,and the clinical symptoms and laboratory findings vary to a certain extent in different age group.

Key words: Dengue fever, Different age group, Clinical features