Journal of Tropical Diseases and Parasitology ›› 2024, Vol. 22 ›› Issue (3): 172-176.doi: 10.3969/j.issn.1672-2302.2024.03.008

• CONTROL STUDIES • Previous Articles     Next Articles

Analysis on the epidemiological characteristics of hand, foot and mouth disease in population aged 6 and over in Changsha, 2013-2022

XIAO Huihui1(), YANG Dong1, DAI Zhihui2, ZHOU Yinzhu1()   

  1. 1. Changsha Center for Disease Control and Prevention, Changsha 410004, Hunan Province, China
    2. Hunan Provincial Center for Disease Control and Prevention
  • Received:2023-12-28 Online:2024-06-20 Published:2024-06-28
  • Contact: ZHOU Yinzhu, E-mail: 375234093@qq.com

Abstract:

Objective To investigate the epidemiological characteristics of hand, foot and mouth disease (HFMD) in the population aged 6 and above in Changsha, Hunan Province, for scientific basis in prevention and control of this infection. Methods The basic information of reported cases of HFMD in Changsha from 2013 to 2022 was obtained through the China Information System for Disease Control and Prevention, and the etiological monitoring data of hand-foot-mouth disease in each county (city, district) were collected. Descriptive epidemiological methods were used to analyze the temporal, regional and population distribution and pathogenic composition of the cases. Results A total of 14 889 cases of HFMD were reported in the population aged 6 and above from 2013 to 2022, which accounted for 5.04% of the total number of HFMD cases. No severe or fatal cases were reported. The average annual reported incidence was 19.54 per 100 000. The proportion of cases in this group showed an increasing trend in the total number of cases (χ2trend=1 658.760, P<0.01). The annual peak of the disease occurred in April to July. Of the reported cases, 8 526 were males, and 6 363 females, with a sex ratio of 1.34∶1. The median age was 7 (6, 10) years old. Maximum age was 91 years old, and the proportion of 6-15 years old was 88.09% (13 116/14 889). The occupation distribution was mainly involved in students, accounting for 55.97% (8 334/14 889). The average annual reported incidence within the urban areas (Yuhua District, Kaifu District, Yuelu District, Furong District and Tianxin District) was 24.70/100 000, which was higher than that in the suburbs (Changsha County, Liuyang City, Ningxiang City and Wangcheng District; 12.75/100 000). Etiological monitoring showed that the positive rate of enterovirus in pathogenic specimens was 50.49% (156/309). The composition of enterovirus A71 (EV-A71), coxasckievirus A16 (CV-A16) and other enteroviruses was 5.77% (9/156), 37.18% (58/156) and 57.05% (89/156), respectively. Conclusion From 2013 to 2022, the proportion of HFMD cases in the population aged 6 and above in Changsha area showed an increasing trend, mainly other enteroviruses. Our findings suggest that attention should be paid to the prevention of HFMD in population aged 6 and above, strengthen the prevention and control measures of hand-foot-mouth disease in primary and secondary schools, and do a good job in monitoring other enterovirus typing.

Key words: Hand, foot and mouth disease, Epidemic characteristics, Etiological characteristics, Changsha City

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