Journal of Tropical Diseases and Parasitology ›› 2015, Vol. 13 ›› Issue (3): 147-149.doi: 10.3969/j.issn.1672-2302.2015.03.007

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Significance of determining monocyte to lymphocyte ratio in evaluation of the progress of gastric cancer

Lu Lin, Chen Yanchun*, Sun Pengyao, Li Yan, Wu Zhili, Sun Xuezhu, Xu Xiuli, Lu Husheng, Liu Tan, Chen Kaixun   

  1. Cancer Center, No. 105 Hospital of PLA, Hefei 230031, China.
  • Online:2015-09-10 Published:2015-09-30

Abstract:

【Abstract】 Objective  To assess the clinical significance of determining the monocyte to lymphocyte ratio (MLR) in evaluating the progress of gastric cancer. Methods  The clinical data were reviewed in 51 cases of gastric cancer treated in our department between January 2007 and January 2013. Peripheral venous blood MLR was calculated in patients before and after initial treatment, periods in disease remission and progress, and the relationship between MLR variation and disease progress were statistically analyzed and compared with the healthy controls. Results  Gastric cancer patients had higher MLR over the healthy control, and lower MLR after surgery, yet higher ratio in disease development after surgery. The difference was significant(P<0.01). Conclusion  MLR is an important indicator in monitoring the disease progress in patients of gastric cancer progression monitoring.

Key words: Monocyte Lymphocyte Ratio, Gastric cancer, Disease progress Monitoring