Abstract:

Objective To explore the effect of using Rongbao to kill Schistosoma japonicum eggs in wild feces and using niclosamide spreading agent to kill miracidium and cercaria in water on the control of schistosomiasis infection source and the interruption the transmission routes. Methods Before the snail infected beach submerged, using 50% Rongbao (feaces：Rongbao=100g︰3g）and 1% niclosamide spreading agent（3ml/m²） to dispose feces and to kill miracidium and cercaria in water respectively every 15 days. Results  Before intervention, the positive rate of feces on beaches of the Yangtze River and the Dongting Lake was 2.22% and 10.23% ，the average density of infected snails was 0.0208 and 0.0417/0.11m², respectively. The infection rate of sentinel mice was 11.11%, and the infection rate of the mice in the control group was 50% in 2012. After intervention, the positive rate of wild feces obviously decreased (χ²=3.64, P＜0.05），the average density of infected snails and the infection rate of sentinel mice decreased to 0. Conclusion  Using Rongbao to dispose wild feces on beaches and combined using niclosamide spreading agent to kill miracidia and cercariae can early control the infection sources of schostosomiasis and can early interrupt the routes of the disease transmission.

Key words: Schistosomiasis, Early intervention,, Rongbao, Niclosamide spreading agent, Wild feces