Evolving trends in the pathogen spectrum of hand, foot and mouth disease in China and strategies for prevention and control

doi:10.20199/j.issn.1672-2302.2025.04.001

Abstract

Abstract:

Hand, foot and mouth disease (HFMD) is a common infection in children caused by various enteroviruses. It is more prevalent in the Western Pacific Region, and remains significant global public health concerns. In recent years, the prevention and control of HFMD in China is facing new challenges with change of the pathogen spectrum of HFMD. This paper reviewed the evolutionary trends of HFMD pathogen spectrum at home and abroad, and detailed the changing characteristics of HFMD pathogen spectrum in China and its impact on clinical diagnosis, treatment, and disease control. Besides, corresponding countermeasure and proposals were put forward from targeted aspects as strengthening the pathogen monitoring, accelerating the research and development of multivalent vaccines, and implementing non-pharmaceutical intervention measures, with an attempt to provide references for the prevention and control of HFMD in the new situation.

Key words: Hand, foot and mouth disease, Pathogen spectrum, Serotype, Prevention and control strategies

CLC Number:

R181.3

ZHANG Zhijie, CHANG Zhaorui. Evolving trends in the pathogen spectrum of hand, foot and mouth disease in China and strategies for prevention and control[J]. Journal of Tropical Diseases and Parasitology, 2025, 23(4): 195-198,215.

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