热带病与寄生虫学

热带病与寄生虫学 ›› 2015, Vol. 13 ›› Issue (3): 150-152.doi: 10.3969/j.issn.1672-2302.2015.03.008

• 论著 • 上一篇    下一篇

2009~2014年河北邢台市A型H3N2流感病原学监测分析

董江华，孙伟明*，闫英民，庞俊华，苏铭，陈风阳，杨度华   

  1. 054000 河北邢台市，邢台市疾病预防控制中心（董江华、孙伟明、庞俊华、苏铭、陈风阳、杨度华），邢台市食品药品监督管理局（闫英民）
  • 出版日期:2015-09-10 发布日期:2015-09-30

Epidemiological surveillance over the influenza A/H3N2 virus in Xingtai City from 2009 to 2014      

Dong Jianghua1, Sun Weiming1*, Yan Yingmin2, Pang Junhua1, Chen Fengyang1, Su Ming1, Yang Duhua1   

  1. 1.Xingtai Center for Disease Control and Prevention, 2.Xingtai Food and Drug Administration, Xingtai 054000, China
  • Online:2015-09-10 Published:2015-09-30

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摘要： 【摘要】 目的  分析2009~2014年邢台市A型H3N2流感病毒流行情况，为科学预防和控制流感提供依据。 方法  采集2009年6月~2014年5月流感样病例（ILI）的咽拭子标本，采用实时荧光定量PCR方法检测A型H3N2流感病毒核酸，以每年6月至次年5月为监测周期进行统计分析。 结果  五个监测周期采集ILI咽拭子标本分别为1 391、514、643、628和1 185份，阳性率分别为6.25%（86/1 391）、7.60%（40/514）、0.31%（2/643）、7.32%（46/628）和1.19%（14/1 185），不同监测周期阳性率差异有统计学意义（χ2=93.728 P<0.01）。高峰期主要出现在1、3和9月，每年4~8月未检测到阳性病例。不同年龄组病毒阳性率差异有统计学意义(χ2=44.595，P<0.01)，5~岁年龄组阳性率（7.94%）最高。 结论  2009~2014年邢台市A型H3N2流感每年均有流行，流行期为当年的9月至次年的3月，高峰期出现在当年的9月至次年的1月。因此为更好防控流感，及时掌握流行趋势，仍需加强监测。

关键词: 甲型H3N2, 流行性感冒, 实时荧光定量PCR

Abstract:

【Abstract】 Objective  To understand the epidemiological tendency of influenza A(H3N2) in Xingtai City from 2009 to 2014 for scientific evidence to prevent and control its spreading. Methods  Throat swab specimens were collected between June 2009 and May 2014 from patients presenting with influenza-like illness (ILI), and subjected to detection of the nucleic acid content of influenza A H3N2 viruses by real-time quantitative fluorescence PCR. The surveillance data obtained from June to the following May were statistically analyzed. Results  Throat swab specimens obtained in 1 391, 514, 643, 628 and 1 185 cases in respective five surveillance cycles were tested, and the positive rates were 6.25%(86/1 391), 7.60%(40/514), 0.31%(2/643), 7.32%(46/628) and 1.19%(14/1 185), respectively. The positive rate was fluctuated significantly in different cycles(χ2=93.728 P<0.01), and was dominated by January, March and September, yet the epidemic was free between April and August within a year. The specimens positive for influenza A(H3N2) virus were statistically different in different age group(χ2=44.595, P<0.01), and highest in the group of five years(7.94%). Conclusion  Influenza A(H3N2) was prevalent in yearly manner in Xintai City from 2009 to 2014, and its epidemic extended from September to following March and peaked between September and following January. However, surveillance needs strengthening in order to timely understand the epidemiological trend for scientific control of this communicable disease.

Key words: Influenza A(H3N2), Influenza, Real-time quantitative PCR