热带病与寄生虫学

热带病与寄生虫学 ›› 2015, Vol. 13 ›› Issue (3): 147-149.doi: 10.3969/j.issn.1672-2302.2015.03.007

• 论著 • 上一篇    下一篇

单核细胞/淋巴细胞比值在胃癌患者病程监测中的意义

陆林，陈延春*，孙鹏摇，李妍，吴志丽，孙雪竹，徐秀理，卢虎生，刘坦，陈开训   

  1. 230031  合肥市，解放军第105医院肿瘤中心
  • 出版日期:2015-09-10 发布日期:2015-09-30

Significance of determining monocyte to lymphocyte ratio in evaluation of the progress of gastric cancer

Lu Lin, Chen Yanchun*, Sun Pengyao, Li Yan, Wu Zhili, Sun Xuezhu, Xu Xiuli, Lu Husheng, Liu Tan, Chen Kaixun   

  1. Cancer Center, No. 105 Hospital of PLA, Hefei 230031, China.
  • Online:2015-09-10 Published:2015-09-30

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摘要： 【摘要】 目的  探讨单核细胞/淋巴细胞比值（monocyte-to-lymphocyte ratio, MLR）在胃癌患者病程监测中的临床价值。 方法  回顾性分析2007年1月至2013年1月期间我院肿瘤科收治的51例胃癌患者的临床资料，计算患者首次治疗前后、病情缓解前后和病情进展前后外周静脉血MLR，统计学分析MLR的变化与胃癌患者病情演变的关系；并设健康对照组。 结果  胃癌患者MLR水平显著高于健康对照组，术后患者MLR较术前水平下降，病情进展（PD）时MLR水平较术后明显增高，上述各组资料差异均有统计学意义（P<0.01）。 结论  MLR在胃癌患者病程监测中具有重要意义。

关键词: 单核细胞/淋巴细胞比值, 胃癌, 病程监测

Abstract:

【Abstract】 Objective  To assess the clinical significance of determining the monocyte to lymphocyte ratio (MLR) in evaluating the progress of gastric cancer. Methods  The clinical data were reviewed in 51 cases of gastric cancer treated in our department between January 2007 and January 2013. Peripheral venous blood MLR was calculated in patients before and after initial treatment, periods in disease remission and progress, and the relationship between MLR variation and disease progress were statistically analyzed and compared with the healthy controls. Results  Gastric cancer patients had higher MLR over the healthy control, and lower MLR after surgery, yet higher ratio in disease development after surgery. The difference was significant(P<0.01). Conclusion  MLR is an important indicator in monitoring the disease progress in patients of gastric cancer progression monitoring.

Key words: Monocyte Lymphocyte Ratio, Gastric cancer, Disease progress Monitoring