Abstract: Visceral leishmaniasis, also known as kala-azar, represents a zoonotic parasitic disease with sandfly as the transmission medium. WHO is advocating an increase to 64（85%） of the number of countries that have achieved the goal of eliminating visceral leishmaniasis as a public health problem by 2030. As one of the zoonosis, the transmission-chain of leishmaniasis is complex. To interrupt transmission from animal hosts to human populations, as well as the establishment of “human-animal-media” co-prevention mechanism is still facing many challenges, which requires cross-sectoral, cross-regional and cross-disciplinary collaboration. The One Health approach, which aims to jointly promote human and animal health, maintain and improve the ecological environment, has advantages in zoonosis prevention and control and can effectively solve this complex public health problem. The aim and strategy for elimination of visceral leishmaniasis according to One Health approach was proposed in this paper, with the role of systematic monitoring and intervention, as well as cross-sectoral, cross-regional and cross-disciplinary collaboration being discussed, in order to provide reference for visceral leishmaniasis control and elimination in our country. 

Key words: Visceral leishmaniasis, Kala-azar, One Health, Control, Elimination, Strategy, Measure