Abstract:

Objective  To investigate the HBsAg, anti-HCV, anti-TP and anti-HIV infection status in the voluntarily donated blood samples in Wuhu City, and to understand the epidemic tendency of infectious diseases in voluntary blood donors for corresponding measures to prevent and control the infections. Methods A retrospective epidemiological investigation was performed in the results of 158020 blood samples collected from 2011 to 2015 in Wuhu area. Results  The total failure rate was 2.37% for the blood donated between 2011 and 2015. The positive rate was 1.13%, 0.30%, 0.79% and 0.16% for  HBsAg, anti -HCV, anti-TP and anti-HIV, respectively, and confirmed positive rate was 0.13% by anti-HIV test. The four infective markers tended to yearly decrease since 2013, and population aged 35 or over had significantly higher positive rate of HBsAg, anti-HCV and anti-TP than those aged under 35. Male population had higher positive rate for HBsAg, and lower positive rate for anti-TP and anti-HCV than females. The difference was significant. The four infective markers were the highest in population associated with agricultural, forestry and stock raising lines as well as workers in manufacturing, drivers and equipment operators. The detected positive rate was 0.085% in voluntary donors in 2015. Conclusion  By current infective status for the blood transmitted disease in Wuhu area, we suggest that some comprehensive measures, including interview, physical examination and screening of the four infective agents before blood donation, rigid quality management system, spreading the knowledge on prevention of the blood transmitted disease and health education, should be taken to ensure safe blood supply.

Key words: Voluntary blood donors, Blood test, Detected positive rate