热带病与寄生虫学

热带病与寄生虫学 ›› 2021, Vol. 19 ›› Issue (1): 28-31.

• 防治研究 • 上一篇    下一篇

571例登革热病例不同年龄组临床特征分析

贾文爽1,李曼2,沈加员2,杨忠平2,毛家荣3,尹小雄4,刘永华4,李杨思琪5,周红宁1,2   

  1. 1. 大理大学病原与媒介生物研究所(普洱分部),云南普洱665000;2. 云南省虫媒传染病防控研究重点实验室,云南省公共卫生与疾病防控协同创新中心,云南省寄生虫病防治所;3. 云南瑞丽市人民医院;4. 云南瑞丽市疾病预防控制中心;5. 昆明医科大学

  • 出版日期:2021-02-20 发布日期:2021-02-04
  • 通信作者: 周红宁,E-mail:zhouhn66@163.com
  • 作者简介:贾文爽,女,硕士在读。研究方向:虫媒传染病防治研究。E-mail:2368598735@qq.com
  • 基金资助:
    国家自然科学基金项目(U1602223);云南省科技重大专项(2017ZF007);国家重大专项项目(2018ZX10101004-003-001);云南省寄
    生虫病防治所虫媒传染病防控关键技术省创新团队(培育)基金(2019HC010);面向南亚东南亚热带病国际科技人员交流与教育培
    训基地基金(20181A106)

Analysis on the clinical characteristics of dengue in 571 cases of different age groups#br#

JIA Wen-shuang1 ,LI Man2 ,SHEN Jia-yuan2, YANG Zhong-ping2 ,MAO Jia-rong3,YIN Xiao-xiong4 ,LIU Yong-hua4 ,LI-YANG Si-qi5, ZHOU Hong-ning1 2#br#   

  1. 1.Institute of Pathogen and Vector Biology Puer Division Dali University, Puer 665000 ,Yunan Province ,China;2 Yunnan Provincial Key Laboratory of Vector-borne Diseases Control and Research Yunnan Provincial Collaborative Innovation Center for Public Health and Disease Prevention and Control Yunnan Institute of Parasitic Diseases 3 Yunnan Ruili People's Hospital;4 Ruili City Center for Disease Control Prevention 5 Kunming Medical University
  • Online:2021-02-20 Published:2021-02-04

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摘要： 目的 分析瑞丽市不同年龄组登革热病例临床特征,为当地医疗卫生部门制订有效的登革热诊疗方案提供依据。方法 将2017-2018年瑞丽市人民医院收治住院的571例登革热病例根据年龄分为未成年组(1~18岁)、成年组(>18~60岁)和老年组(>60岁),对3组临床症状和体征、实验室生化指标进行分析。结果 571例登革热患者中,未成年组117 例,成年组422 例,老年组32 例,以成年组为主。三个年龄组登革热患者均以发热(97.0%)、乏力(84.2%)、纳差(82.3%)、头痛(76.0%)和全身肌肉酸痛(74.1%)为主要临床症状。其中,成年组头
痛、全身肌肉关节酸痛、乏力、纳差等症状发生率高于未成年组,老年组发热发生率最低。实验室生化指标异常主要表现在WBC减少(52.4%)和AST升高(53.4%)。未成年组血糖、电解质异常发生率较成年组及老年组低,但碱性磷酸酶和总胆红素升高的发生率较成年组及老年组高,未成年组心肌损害发生率高;成年组WBC减少的发生率最低;老年组PLT减少的发生率最高,肾功能损害发生率高。结论 云南省瑞丽市人民医院登革热病毒感染患者主要为成年人,不同年龄组临床症状及其实验室生化指标特征不同。

关键词: 登革热, 不同年龄组, 临床特征

Abstract: Objective To retrospectively analyze the clinical characteristics of dengue in different age group in Ruili city from 2017 to 2018 for evidence for local health administrations to plan effective measures in diagnosis and treatment of this infection.Methods A total of 571 cases of dengue treated in Ruili People’s Hospital from 2017 to 2018 were divided into minor group(1~18 years),adult group (>18~60 years) and elderly group (>60 years).Analysis was performed regarding the clinical symptoms,signs and laboratory findings in the three groups.Results Of the 571 cases,117 were minors,422 adults and 32 elderly.The clinical symptoms were dominated by fever (97.0%),fatigue( 84.2%),poor appetite(82.3%),headache(76.0%) and systemic muscle soreness(74.1%),and headache, systemic muscle soreness,fatigue and poor appetite were more common in adult group than in minor group.Fever was few seen in elderly group.Abnormal biochemical indicators were primarily associated with decreased WBC (52.4%) and increased AST(53.4%).Minors had lower incidence of abnormal blood glucose and electrolyte,yet had elevated levels of alkaline phosphatase and total bilirubin compared to adults and the elderly.Incidence of myo-cardial damage was the highest in minors group,and decreased WBC was the lowest in adult group.Elderly patients had the highest incidence of PLT decrease and damage of renal function.Conclusion The patients with dengue virus infection treated in Ruili People's Hospital of Yunnan Province are mainly adults,and the clinical symptoms and laboratory findings vary to a certain extent in different age group.

Key words: Dengue fever, Different age group, Clinical features

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