热带病与寄生虫学

热带病与寄生虫学 ›› 2020, Vol. 18 ›› Issue (2): 102-104.

• 临床研究 • 上一篇    下一篇

368 例输入性疟疾的临床分析

徐瑗瑗,李磊
  

  1. 中国科学技术大学附属第一医院感染病科,合肥 230001
  • 出版日期:2020-06-10 发布日期:2020-05-27
  • 作者简介:徐瑗瑗,女,硕士,副主任医师,研究方向:感染性疾病的临床诊治。
  • 基金资助:
    安徽省自然科学基金(1208085QH147)

Clinical analysis of imported malaria in 368 cases 

XU Yuan-yuan, LI Lei    

  1. Department of Infectious Disease, the First Affiliated Hospital of University of Science and Technology of China, Hefei 230001, China
  • Online:2020-06-10 Published:2020-05-27

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摘要： 目的 分析输入性疟疾患者的流行病学和临床特点,为临床诊治提供参考。 方法 对本院 2007 年 1 月-2019 年 12 月收治的 368 例输入性疟疾患者的流行病学及临床特征进行回顾性分析。 结果 368 例输入性疟疾病例均为非洲输入,所有患者均经实验室检查明确诊断。 其中,恶性疟 103 例,间日疟 95 例,卵形疟 31 例,三日疟 112,混合感染 27 例;男性 366 例(99. 5%);所有患者均有畏寒、发热症状;97. 6%的病例在发病后 5 d 内确诊,并得到及时诊治;所有收治的患者中,治愈 364 例(98. 9%)、死亡 4 例(1. 1%)。 予以蒿甲醚加大剂量加大疗程治疗,无明显副作用。 结论 临床医生应警惕输入性疟疾的病例,做到早期诊断,及时治疗,改善预后。

关键词: 输入性疟疾, 诊断, 治疗

Abstract: Objective To analyze the epidemiological and clinical characteristics of imported malaria for evidence in clinical diagnosis and treatment. Methods Retrospective analysis was performed regarding the epidemiological and clinical characteristics in 368 cases of imported malaria admitted to and treated in our hospital between January 2007 and December 2019. Results The 368 patients were imported malaria from African counties, and diagnosed by laboratory examination, in whom 103 were infected with Plasmodium falciparum, 95 with Plasmodium vivax, 31 with Plasmodium ovale, 112 with  Plasmodium malariae and another 27 with mixed infection. 366 cases were males(99. 5% ). All patients had symptoms of chills and fever. 97. 6% of the patients were diagnosed within 5 days after onset, and received timely treatment. 364 patients were cured(98. 9% ), and death occurred in 4(1. 1% ). Artemtherin was administered in increased dose and prolonged course without obvious adverse effects. Conclusion Clinicians should be alert to cases of imported malaria. Early diagnosis and prompt treatment can improve the prognosis of patients.

Key words: Imported malaria, Diagnosis, Treatment

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