热带病与寄生虫学

热带病与寄生虫学 ›› 2014, Vol. 12 ›› Issue (2): 81-82.doi: 10.3969/j.issn.1672-2302.2014.02.007

• 论著 • 上一篇    下一篇

晚期血吸虫病肝硬化患者凝血功能检测分析

牛长生,余永辉   

  1. 247230 安徽东至县，东至县血吸虫病防治站
  • 出版日期:2014-06-10 发布日期:2014-08-13

Analysis of blood coagulation function in patients with cirrhosis due to advanced schistosomiasis

Niu Changsheng,Yu Yonghui .   

  1. Dongzhi County Station Of Schistosomiasis Control , Dongzhi 247230, China.
  • Online:2014-06-10 Published:2014-08-13

被引次数

9

摘要： 目的 对比检测晚期血吸虫病与慢性血吸虫病患者的凝血指标，探讨晚血病人的凝血功能机制，及时监测晚血病人的出血倾向并为临床指导用药提供依据。方法 运用国产雷杜RT-2204C 血凝仪检测37 例晚血病人和80 例慢血病人的血浆凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）和凝血酶时间（TT）。结果 晚血病人PT、APTT 和TT 值均大于慢血病人，差异有统计学意义（P 均<0.01）。结论 晚血患者凝血功能明显异常，处于低凝状态且纤溶系统受损，检测该指标对监测晚血病人出血倾向与指导临床用药具有重要的意义。

关键词: 晚期血吸虫病, 凝血, 凝血酶原时间, 活化部分凝血活酶时间, 凝血酶时间

Abstract:

Objective To detect the indexes of blood coagulation in patients with advanced schistosomiasis (AS) compared with chronic schistosomiasis (CS), probe its coagulation mechanism, monitor the bleeding tendency timely and provide basis for clinical treatment. Methods Prothrombin time (PT), activated partial thromboplastin time (APTT) and thrombin time (TT) of 37 patients with AS and 80 with CS were detected by Rayto RT- 2204C coagulation analyzer. Results PT, APTT and TT of patients with AS were obvious higher than patients with CS（P<0.01）.Conclusion The blood coagulation function of patients with AS is obvious abnormal. Detecting the indexes of blood coagulation is significant to monitoring the bleeding tendency and instructing the clinical medication for patients with AS.

Key words: Advanced schistosomiasis, Blood coagulation, PT, APTT, Thrombin time