热带病与寄生虫学

热带病与寄生虫学 ›› 2013, Vol. 11 ›› Issue (4): 200-203.doi: 10.3969/j.issn.1672-2302.2013.04.005

• 论著 • 上一篇    下一篇

血吸虫病易感地带早期干预的研究

易平，魏望远* ，李华中，郭家钢，郑灿军，朱蓉，鲍子平，余晴，刘宗传，丁良，蔡斌，李君祥   

  1. 湖南省血吸虫病防治所（易平、魏望远、刘宗传、丁良），中国CDC（李华中、郑灿军） ，中国CDC寄生虫病预防控制所（郭家钢、朱蓉、鲍子平、余晴），湖南省君山区柳林血防站（蔡斌、李君祥）
  • 出版日期:2013-04-25 发布日期:2014-02-19
  • 基金资助:

    中国CDC专项（ID：201104004）、国家科技重大专项资助项目（2012ZX10004909）

Study on early warning and intervention on schistosomiasis in susceptible areas

Yi Ping1, Wei Wangyuan1, Li Huazhong2, Guo Jiagang3, Zheng Canjun2, Zhu Rong3, Bao Ziping3, Yu Qing3, Liu Zongchuan1,Ding Liang1, Cai Bing4, Li Junxiang4   

  1. 1. Hunan Institute of Schistosomiasis Control, yueyang 414000, China. 2. Chinese Center for Disease Control and Prevention.   3. National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention.   4. Schistosomiasis Control Station of Junshan District in Hunan Province
  • Online:2013-04-25 Published:2014-02-19

被引次数

3

摘要： 目的  探索荣宝杀灭野粪中血吸虫卵和氯硝柳胺展膜剂杀水体中毛（尾）蚴控制传染源和阻断传播途径的效果。 方法  水淹有螺洲滩前，每15 d用50%荣宝处理外洲野粪（粪︰药=100g︰3g）和1%氯硝柳胺展膜剂（3ml/m2）处理水体毛（尾）蚴。 结果  干预前，长江和洞庭湖洲滩野粪阳性率分别2.22%和10.23%，感染螺平均密度0.020 8和0.041 7只/0.11m2，哨鼠感染率11.11%，2012年对照组哨鼠感染率50%；干预后野粪阳性率显著下降，差异有统计学意义（χ2=3.64，P＜0.05），感染螺平均密度和哨鼠感染率均下降至0。 结论联合使用荣宝处理洲滩野粪和氯硝柳胺展膜剂杀灭水体中毛（尾）蚴，具有早期控制血吸虫病传染源和阻断传播途径的作用。

关键词: 血吸虫病, 早期干预, 荣宝, 氯硝柳胺展剂, 野粪

Abstract:

Objective To explore the effect of using Rongbao to kill Schistosoma japonicum eggs in wild feces and using niclosamide spreading agent to kill miracidium and cercaria in water on the control of schistosomiasis infection source and the interruption the transmission routes. Methods Before the snail infected beach submerged, using 50% Rongbao (feaces：Rongbao=100g︰3g）and 1% niclosamide spreading agent（3ml/m2） to dispose feces and to kill miracidium and cercaria in water respectively every 15 days. Results  Before intervention, the positive rate of feces on beaches of the Yangtze River and the Dongting Lake was 2.22% and 10.23% ，the average density of infected snails was 0.0208 and 0.0417/0.11m2, respectively. The infection rate of sentinel mice was 11.11%, and the infection rate of the mice in the control group was 50% in 2012. After intervention, the positive rate of wild feces obviously decreased (χ2=3.64, P＜0.05），the average density of infected snails and the infection rate of sentinel mice decreased to 0. Conclusion  Using Rongbao to dispose wild feces on beaches and combined using niclosamide spreading agent to kill miracidia and cercariae can early control the infection sources of schostosomiasis and can early interrupt the routes of the disease transmission.

Key words: Schistosomiasis, Early intervention,, Rongbao, Niclosamide spreading agent, Wild feces