热带病与寄生虫学

热带病与寄生虫学 ›› 2025, Vol. 23 ›› Issue (5): 313-318.

• 综述 • 上一篇    

棘球绦虫基因分型研究进展

李小璐，郭邦成，高建炜，海娥，杨聪，田金花，白楠，田瑜琳   

  1. 宁夏回族自治区疾病预防控制中心，宁夏回族自治区预防医学科学院，宁夏 银川 750004
  • 收稿日期:2025-05-30 出版日期:2025-10-20 发布日期:2025-11-28
  • 通信作者: 郭邦成，E-mail: gbc_1984@qq.com
  • 作者简介:李小璐，女，硕士，主管技师，研究方向：棘球蚴病检测及预防控制。E-mail: 952229546@qq.com
  • 基金资助:
    宁夏卫生健康委青年科技培育项目（2023-NWKYP-036）

Research advances in genotyping of Echinococcus

LI Xiaolu, GUO Bangcheng, GAO Jianwei, HAI E, YANG Cong, TIAN Jinhua, BAI Nan, TIAN Yulin   

  1. Ningxia Hui Autonomous Region Center for Disease Control and Prevention, Ningxia Hui Autonomous Region Academy of Preventive Medicine, Yinchuan 750004, Ningxia Hui Autonomous Region, China
  • Received:2025-05-30 Online:2025-10-20 Published:2025-11-28

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摘要： 棘球蚴病是由棘球绦虫幼虫（棘球蚴）寄生于中间宿主肝、肺等组织器官引发的一类人兽共患寄生虫病，其在全球范围流行，不仅严重危害人体健康，还对畜牧业发展造成严重影响。近年来，随着分子生物学技术的发展，棘球绦虫基因分型研究取得了显著进展。本文对棘球绦虫基因分型技术、主要的基因分型方法、两种重要棘球绦虫的基因分型及全球流行概况进行综述，并对未来的发展方向进行展望，为进一步开展棘球蚴病相关防治研究提供参考。

关键词: 棘球绦虫；基因分型；细粒棘球绦虫；多房棘球绦虫 

Abstract: Echinococcosis, caused by the larvae of Echinococcus (hydatid cysts) parasitizing in the liver, lung and other tissues and organs of intermediate hosts, is a globally prevalent zoonotic parasitic disease. It not only seriously endangers human health but also exerts a significant impact on the development of animal husbandry. In recent years, research on the genotyping of Echinococcus has advanced with the progress of molecular biology techniques. In this article, we reviewed the genotyping techniques of Echinococcus, major genotyping methods, research progress on the genotyping of two important Echinococcus species and their global epidemic status, with an attempt to offer an insight into the research in future and provide references for better understanding and control of echinococcosis.

Key words: Echinococcus, Genotyping; Echinococcus granulosus, Echinococcus multilocularis

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