热带病与寄生虫学

热带病与寄生虫学 ›› 2016, Vol. 14 ›› Issue (4): 211-214.doi: 10.3969/j.issn.1672-2302.2016.04.009

• 论著 • 上一篇    下一篇

芜湖市无偿献血者血液感染因子检测结果回顾性分析

成国明,赵茹,张正红,豆正东,方艳姣,张敏   

  1. 241000 安徽芜湖市，芜湖市疾病预防控制中心（成国明、张正红、豆正东、方艳姣、张敏），芜湖市中心血站（赵茹）
  • 出版日期:2016-12-10 发布日期:2017-01-02

Retrospective analysis on the source blood infection agents from voluntarily donated blood samples in Wuhu City

Cheng Guoming1, Zhao Ru2, Zhang Zhenghong1, Dou Zhengdong1, Fang Yanjiao1, Zhang Min1   

  1. 1. Wuhu Center for Disease Control and Prevention, Wuhu 241000, China. 2. Wuhu Center Blood Station, Wuhu 241000, China.
  • Online:2016-12-10 Published:2017-01-02

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摘要： 目的 通过对芜湖市无偿献血者HBsAg、抗-HCV 、抗-TP、抗-HIV检测结果的分析，了解无偿献血者经血传播疾病的感染状况，为采取相应措施提供依据。 方法  对芜湖市2011~2015年无偿献血者血液标本158 020（人）份的检测结果进行回顾性统计分析。结果 芜湖市2011~2015年无偿献血者血液感染因子总不合格率为2.37％，HBsAg、抗-HCV、抗-TP、抗-HIV阳性率分别为1.13%、0.30%、0.79%、0.16%，抗-HIV确证阳性率为0.13‰；2013年起，四项感染因子阳性率均呈逐年下降趋势。35岁以上年龄组HBsAg、抗-HCV、抗-TP阳性率远高于35岁以下年龄组。HBsAg检测阳性率男性大于女性，抗-TP、抗-HCV女性大于男性，差异有统计学意义。不同职业人群中，农、林、牧等生产人员和生产、运输设备操作人员四项感染因子阳性率较高。2015年开展的感染因子核酸检测阳性检出率为0.085%。 结论  根据芜湖市的实际情况，加强献血前征询和体检、全面开展四项感染因子核酸检测，建立完善的质量管理体系，开展有关输血传染病防治方法的宣传、教育，保障血液安全。

关键词: 无偿献血者, 血液检测, 检测阳性率

Abstract:

Objective  To investigate the HBsAg, anti-HCV, anti-TP and anti-HIV infection status in the voluntarily donated blood samples in Wuhu City, and to understand the epidemic tendency of infectious diseases in voluntary blood donors for corresponding measures to prevent and control the infections. Methods A retrospective epidemiological investigation was performed in the results of 158020 blood samples collected from 2011 to 2015 in Wuhu area. Results  The total failure rate was 2.37% for the blood donated between 2011 and 2015. The positive rate was 1.13%, 0.30%, 0.79% and 0.16% for  HBsAg, anti -HCV, anti-TP and anti-HIV, respectively, and confirmed positive rate was 0.13% by anti-HIV test. The four infective markers tended to yearly decrease since 2013, and population aged 35 or over had significantly higher positive rate of HBsAg, anti-HCV and anti-TP than those aged under 35. Male population had higher positive rate for HBsAg, and lower positive rate for anti-TP and anti-HCV than females. The difference was significant. The four infective markers were the highest in population associated with agricultural, forestry and stock raising lines as well as workers in manufacturing, drivers and equipment operators. The detected positive rate was 0.085% in voluntary donors in 2015. Conclusion  By current infective status for the blood transmitted disease in Wuhu area, we suggest that some comprehensive measures, including interview, physical examination and screening of the four infective agents before blood donation, rigid quality management system, spreading the knowledge on prevention of the blood transmitted disease and health education, should be taken to ensure safe blood supply.

Key words: Voluntary blood donors, Blood test, Detected positive rate